STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F38B6.6Protein O-mannosyl-transferase TMTC1; Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. (690 aa)    
Predicted Functional Partners:
T27F7.4
Mannosyltransferase.
   
  
 0.926
inst-1
INTegrator complex Subunit homolog.
    
 
 0.924
R02D3.4
INTegrator complex Subunit homolog.
    
 
 0.846
Y92H12A.4
INTegrator complex Subunit homolog.
    
 
 0.783
nduo-4
NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
   
 
 0.738
chs-2
Chitin synthase chs-2; May be involved in chitin synthesis in the pharynx during larval development; Belongs to the chitin synthase family. Class IV subfamily.
  
 0.660
chs-1
Chitin synthase chs-1; Essential for the embryonic synthesis of chitin, a component of the eggshell.
  
 0.654
dic-1
VWFA domain-containing protein.
   
 
 0.611
osm-12
Bardet-Biedl syndrome 7 protein homolog; Component of the BBSome complex (By similarity). The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia (By similarity). The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function (By similarity). Required for proper BBSome complex assembly and its ciliary localization (By similarity). Required for cilia biogenesis and both the assembly and movement of intraflagellar transport proteins along the ciliary axoneme. Plays a role in [...]
   
 
 0.608
F19F10.12
Beta-Casp domain-containing protein.
  
 
 0.598
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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