hlh-17 protein (Caenorhabditis elegans) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

hlh-17

BHLH domain-containing protein. (101 aa)

Predicted Functional Partners:

ptr-10

0.811

vab-3

0.708

mls-2

0.696

cima-1

0.694

col-177

0.694

col-53

0.694

F11C7.2

0.691

swip-10

0.624

sro-1

0.619

hlh-14

0.617

Your Current Organism:

Caenorhabditis elegans

NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F11C7.2	col-177	F11C7.2.1	F59F3.2.1	Uncharacterized protein.	COLlagen.	0.894
F11C7.2	col-53	F11C7.2.1	M01A12.1.1	Uncharacterized protein.	COLlagen.	0.894
F11C7.2	hlh-17	F11C7.2.1	F38C2.2.1	Uncharacterized protein.	BHLH domain-containing protein.	0.691
cima-1	hlh-17	F45E4.11.1	F38C2.2.1	MFS domain-containing protein.	BHLH domain-containing protein.	0.694
col-177	F11C7.2	F59F3.2.1	F11C7.2.1	COLlagen.	Uncharacterized protein.	0.894
col-177	col-53	F59F3.2.1	M01A12.1.1	COLlagen.	COLlagen.	0.506
col-177	hlh-17	F59F3.2.1	F38C2.2.1	COLlagen.	BHLH domain-containing protein.	0.694
col-53	F11C7.2	M01A12.1.1	F11C7.2.1	COLlagen.	Uncharacterized protein.	0.894
col-53	col-177	M01A12.1.1	F59F3.2.1	COLlagen.	COLlagen.	0.506
col-53	hlh-17	M01A12.1.1	F38C2.2.1	COLlagen.	BHLH domain-containing protein.	0.694
hlh-14	hlh-17	C18A3.8.1	F38C2.2.1	BHLH domain-containing protein.	BHLH domain-containing protein.	0.617
hlh-14	vab-3	C18A3.8.1	F14F3.1a.1	BHLH domain-containing protein.	Homeobox domain-containing protein.	0.453
hlh-17	F11C7.2	F38C2.2.1	F11C7.2.1	BHLH domain-containing protein.	Uncharacterized protein.	0.691
hlh-17	cima-1	F38C2.2.1	F45E4.11.1	BHLH domain-containing protein.	MFS domain-containing protein.	0.694
hlh-17	col-177	F38C2.2.1	F59F3.2.1	BHLH domain-containing protein.	COLlagen.	0.694
hlh-17	col-53	F38C2.2.1	M01A12.1.1	BHLH domain-containing protein.	COLlagen.	0.694
hlh-17	hlh-14	F38C2.2.1	C18A3.8.1	BHLH domain-containing protein.	BHLH domain-containing protein.	0.617
hlh-17	mls-2	F38C2.2.1	C39E6.4.1	BHLH domain-containing protein.	Homeobox domain-containing protein.	0.696
hlh-17	ptr-10	F38C2.2.1	F55F8.1.2	BHLH domain-containing protein.	SSD domain-containing protein.	0.811
hlh-17	sro-1	F38C2.2.1	D1022.6.1	BHLH domain-containing protein.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.619