STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fbxb-3F-box domain-containing protein. (361 aa)    
Predicted Functional Partners:
rpn-8
MPN domain-containing protein.
      
 0.660
fbxb-83
FBA_2 domain-containing protein.
   
   
0.592
fbxb-13
F-box domain-containing protein.
   
   
0.584
zyg-11
Early embryogenesis protein zyg-11; Acts as target recruitment subunit in the E3 ubiquitin ligase complex zyg-11-cul-2-elc-1. Required for metaphase to anaphase transition and M phase exit at meiosis II. Regulates polarity establishment.
      
 0.567
fbxc-18
F-box C protein.
   
    0.566
fbxb-84
F-box domain-containing protein.
   
   
0.553
fbxb-41
F-box domain-containing protein.
   
    0.551
btb-11
BTB domain-containing protein.
   
    0.550
Y106G6D.2
Uncharacterized protein.
   
    0.548
dsl-2
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
   
    0.546
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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