node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C09D4.1 | C27A7.1 | C09D4.1a.1 | C27A7.1a.1 | Uncharacterized MFS-type transporter C09D4.1; Belongs to the major facilitator superfamily. Feline leukemia virus subgroup C receptor (TC 2.A.1.28.1) family. | Ectonucleotide pyrophosphatase/phosphodiesterase C27A7.1; Probable phosphodiesterase. | 0.818 |
C09D4.1 | ZK795.3 | C09D4.1a.1 | ZK795.3.1 | Uncharacterized MFS-type transporter C09D4.1; Belongs to the major facilitator superfamily. Feline leukemia virus subgroup C receptor (TC 2.A.1.28.1) family. | Brix domain-containing protein ZK795.3. | 0.891 |
C09D4.1 | marc-3 | C09D4.1a.1 | C17E4.3.1 | Uncharacterized MFS-type transporter C09D4.1; Belongs to the major facilitator superfamily. Feline leukemia virus subgroup C receptor (TC 2.A.1.28.1) family. | RING-CH-type domain-containing protein. | 0.920 |
C09D4.1 | tag-30 | C09D4.1a.1 | F38H4.7.2 | Uncharacterized MFS-type transporter C09D4.1; Belongs to the major facilitator superfamily. Feline leukemia virus subgroup C receptor (TC 2.A.1.28.1) family. | BTB domain-containing protein. | 0.666 |
C09D4.1 | tbc-18 | C09D4.1a.1 | F41D9.1.1 | Uncharacterized MFS-type transporter C09D4.1; Belongs to the major facilitator superfamily. Feline leukemia virus subgroup C receptor (TC 2.A.1.28.1) family. | TBC (Tre-2/Bub2/Cdc16) domain family. | 0.803 |
C27A7.1 | C09D4.1 | C27A7.1a.1 | C09D4.1a.1 | Ectonucleotide pyrophosphatase/phosphodiesterase C27A7.1; Probable phosphodiesterase. | Uncharacterized MFS-type transporter C09D4.1; Belongs to the major facilitator superfamily. Feline leukemia virus subgroup C receptor (TC 2.A.1.28.1) family. | 0.818 |
C27A7.1 | ZK795.3 | C27A7.1a.1 | ZK795.3.1 | Ectonucleotide pyrophosphatase/phosphodiesterase C27A7.1; Probable phosphodiesterase. | Brix domain-containing protein ZK795.3. | 0.697 |
C27A7.1 | marc-3 | C27A7.1a.1 | C17E4.3.1 | Ectonucleotide pyrophosphatase/phosphodiesterase C27A7.1; Probable phosphodiesterase. | RING-CH-type domain-containing protein. | 0.810 |
C27A7.1 | tag-30 | C27A7.1a.1 | F38H4.7.2 | Ectonucleotide pyrophosphatase/phosphodiesterase C27A7.1; Probable phosphodiesterase. | BTB domain-containing protein. | 0.699 |
C27A7.1 | tbc-18 | C27A7.1a.1 | F41D9.1.1 | Ectonucleotide pyrophosphatase/phosphodiesterase C27A7.1; Probable phosphodiesterase. | TBC (Tre-2/Bub2/Cdc16) domain family. | 0.459 |
ZK795.3 | C09D4.1 | ZK795.3.1 | C09D4.1a.1 | Brix domain-containing protein ZK795.3. | Uncharacterized MFS-type transporter C09D4.1; Belongs to the major facilitator superfamily. Feline leukemia virus subgroup C receptor (TC 2.A.1.28.1) family. | 0.891 |
ZK795.3 | C27A7.1 | ZK795.3.1 | C27A7.1a.1 | Brix domain-containing protein ZK795.3. | Ectonucleotide pyrophosphatase/phosphodiesterase C27A7.1; Probable phosphodiesterase. | 0.697 |
ZK795.3 | marc-3 | ZK795.3.1 | C17E4.3.1 | Brix domain-containing protein ZK795.3. | RING-CH-type domain-containing protein. | 0.882 |
ZK795.3 | tag-30 | ZK795.3.1 | F38H4.7.2 | Brix domain-containing protein ZK795.3. | BTB domain-containing protein. | 0.805 |
ZK795.3 | tbc-18 | ZK795.3.1 | F41D9.1.1 | Brix domain-containing protein ZK795.3. | TBC (Tre-2/Bub2/Cdc16) domain family. | 0.620 |
csn-2 | csn-5 | B0025.2.1 | B0547.1.1 | COP9 signalosome complex subunit 2; Essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of the SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF. The CSN complex plays an essential role in embryogenesis and oogenesis and is required to regulate microtubule stability in the early embryo. Mediates mei-3/katanin targeting for degradation at the mei [...] | COP9 signalosome complex subunit 5; Probable protease subunit of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of the SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF. In the complex, it probably acts as the catalytic center that mediates the cleavage of Nedd8 from cullins. It however has no metalloprotease activity by itself and requires the other subunits of [...] | 0.999 |
csn-2 | csn-6 | B0025.2.1 | Y67H2A.6b.1 | COP9 signalosome complex subunit 2; Essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of the SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF. The CSN complex plays an essential role in embryogenesis and oogenesis and is required to regulate microtubule stability in the early embryo. Mediates mei-3/katanin targeting for degradation at the mei [...] | COP9 signalosome complex subunit 6; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of the SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF. The CSN complex plays an essential role in embryogenesis and oogenesis and is required to regulate microtubule stability in the early embryo. Mediates mei-3/katanin targeting for degradation at the meiosis to mi [...] | 0.999 |
csn-2 | cul-3 | B0025.2.1 | Y108G3AL.1a.3 | COP9 signalosome complex subunit 2; Essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of the SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF. The CSN complex plays an essential role in embryogenesis and oogenesis and is required to regulate microtubule stability in the early embryo. Mediates mei-3/katanin targeting for degradation at the mei [...] | Cullin-3; Probable core component of multiple cullin-RING-based BCB (BTB-CUL3-BTB) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Probably acts as a scaffold protein which may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. Required to target mei-3/katanin for degradation at the meiosis to mitosis transition via its neddylation and deneddylation. Functions in ubiquitin-mediated degradation of CKIs to target cki-1 for degradation. Regulates microtubule st [...] | 0.837 |
csn-2 | tag-30 | B0025.2.1 | F38H4.7.2 | COP9 signalosome complex subunit 2; Essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of the SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF. The CSN complex plays an essential role in embryogenesis and oogenesis and is required to regulate microtubule stability in the early embryo. Mediates mei-3/katanin targeting for degradation at the mei [...] | BTB domain-containing protein. | 0.641 |
csn-5 | csn-2 | B0547.1.1 | B0025.2.1 | COP9 signalosome complex subunit 5; Probable protease subunit of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of the SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF. In the complex, it probably acts as the catalytic center that mediates the cleavage of Nedd8 from cullins. It however has no metalloprotease activity by itself and requires the other subunits of [...] | COP9 signalosome complex subunit 2; Essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of the SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF. The CSN complex plays an essential role in embryogenesis and oogenesis and is required to regulate microtubule stability in the early embryo. Mediates mei-3/katanin targeting for degradation at the mei [...] | 0.999 |