STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
add-1Adducin-related protein 1; Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. (732 aa)    
Predicted Functional Partners:
act-5
ACTin.
   
 
 0.969
R08D7.7
Uncharacterized sugar kinase R08D7.7; Belongs to the FGGY kinase family.
  
 
 0.915
C01G10.9
Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
  
 
 0.908
tpi-1
Triosephosphate isomerase; Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis.
  
 
 0.873
F58H1.8
Uncharacterized protein.
  
 
 0.859
tkt-1
Transket_pyr domain-containing protein.
  
 
 0.855
unc-44
Uncharacterized protein.
   
 
 0.854
add-2
Adducin-related protein 2; Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network; Belongs to the aldolase class II family. Adducin subfamily.
  
  
0.831
fbp-1
FBPase domain-containing protein; Belongs to the FBPase class 1 family.
   
 
 0.823
T25B9.9
6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
     
 0.790
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.