STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ntc-1Nematocin; Ligand for the G-protein coupled receptor ntr-1. Plays a role in gustatory associative learning. Also plays a role in male mating behavior. (103 aa)    
Predicted Functional Partners:
ntr-2
Nematocin receptor 2; Not directly activated by nematocin. May modulate activity of the nematocin receptor ntr- 1, leading to reduced intracellular cAMP production. Plays a role in male mating behavior. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
      
 0.892
ntr-1
Nematocin receptor 1; Receptor for nematocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. The activity of this receptor may be modulated by ntr-2, leading to reduced intracellular cAMP production. Plays a role in gustatory associative learning. Also plays a role in male mating behavior ; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
      
 0.852
rgba-1
Regulatory Gene for Behavioral Aging.
      
 0.550
frpr-4
G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.
      
 0.532
aqp-2
AQuaPorin or aquaglyceroporin related; Belongs to the MIP/aquaporin (TC 1.A.8) family.
      
 0.531
npr-28
G_PROTEIN_RECEP_F1_2 domain-containing protein.
   
  
 0.479
flp-11
FMRFamide-like neuropeptides 11; FMRFamides and FMRFamide-like peptides are neuropeptides. [ASGGMRNALVRF-amide]: Acts as a ligand for the npr-22 receptor in vitro; Belongs to the FARP (FMRFamide related peptide) family.
   
  
 0.475
pdf-1
PDF (Arthropod Pigment Dispersing Factor) homolog.
   
  
 0.424
flp-25
FMRF-Like Peptide.
   
  
 0.406
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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