STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F39F10.3Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (298 aa)    
Predicted Functional Partners:
cdc-7
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
  
 
 0.795
mlk-1
Mitogen-activated protein kinase kinase kinase mlk-1; Serine/threonine-protein kinase which, by phosphorylating and activating mek-1, plays an important role in the activation of the JNK pathway composed of mlk-1, mek-1 and kgb-1. Involved in the response to environmental stress such as heavy metals. By activating the JNK pathway downstream of tyrosine receptor svh-2, plays a role in axon regeneration after injury.
    
 
 0.674
lsy-27
Uncharacterized protein.
   
   0.458
rgs-9
Regulator of G-protein signaling rgs-9.
   
   0.413
T15B12.2
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
  
     0.412
lin-15B
Protein lin-15B; Synthetic multivulva (synMuv) class B protein. SynMuv proteins are required to repress the induction of vulval development. Acts redundantly with SynMuv class A protein lin-15A to negatively regulate vulval development. Regulates let-23 basal activity.
   
 
 0.405
H05L14.1
Uncharacterized protein.
      
0.402
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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