STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ugt-61UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (530 aa)    
Predicted Functional Partners:
Y105E8B.9
Uncharacterized protein.
     
 0.925
gad-3
Probable aldehyde oxidase gad-3; May be involved in the metabolism of 1-methylnicotinamide (MNA). Linked to regulation of longevity through generation of reactive oxygen species, where it probably functions in a pathway downstream of the sirtuin sir-2.1 and the nicotinamide N-methyltransferase anmt-1. Belongs to the xanthine dehydrogenase family.
 
 
 
 0.909
sqv-4
UDP-glucose 6-dehydrogenase; Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
     
 0.903
C54E4.5
Uncharacterized protein.
   
 
  0.900
D2063.1
PKS_ER domain-containing protein; Belongs to the zinc-containing alcohol dehydrogenase family.
   
 
 0.807
glct-4
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family.
      
 0.696
F48D6.4
Uncharacterized protein.
      
 0.695
K01D12.15
Uncharacterized protein.
      
 0.691
sodh-1
Alcohol dehydrogenase 1; Belongs to the zinc-containing alcohol dehydrogenase family.
   
 
 0.680
cyp-14A3
CYtochrome P450 family; Belongs to the cytochrome P450 family.
   
 
 0.671
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.