STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
syp-3Uncharacterized protein. (224 aa)    
Predicted Functional Partners:
syp-4
Synaptonemal complex protein 4; Constitutes an element of the transverse filaments of the synaptonemal complex (SC), formed between homologous chromosomes during meiotic prophase I, and is required for the assembly of the central region of the SC. Required for chromosome synapsis and chiasma formation between homologous chromosomes during meiosis, mechanisms that are crucial for crossover formation and meiotic recombination.
   
 
 0.985
syp-2
Uncharacterized protein.
   
  
 0.981
him-3
HORMA domain-containing protein.
   
  
 0.956
htp-1
HORMA domain-containing protein.
   
  
 0.955
htp-3
HORMA domain-containing protein.
   
  
 0.938
spo-11
Meiotic recombination protein spo-11; Required for meiotic recombination. Mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination.
   
  
 0.883
htp-2
HORMA domain-containing protein.
   
  
 0.881
cosa-1
CrossOver Site Associated.
   
  
 0.858
Y54E10A.12
Uncharacterized protein.
   
  
 0.857
zhp-3
RING-type domain-containing protein.
   
  
 0.846
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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