STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F40F8.4Uncharacterized protein. (195 aa)    
Predicted Functional Partners:
C33G8.4
Uncharacterized protein.
   
    0.764
F20A1.1
Uncharacterized protein.
   
    0.610
ZK822.4
DUF148 domain-containing protein.
   
    0.591
tag-209
Putative protein tag-209.
   
    0.546
F53F4.13
Uncharacterized protein.
   
    0.540
F07C6.3
Uncharacterized protein.
   
    0.538
far-8
Fatty Acid/Retinol binding protein.
   
    0.538
T02B11.3
Uncharacterized protein.
   
    0.538
cdc-14
Tyrosine-protein phosphatase cdc-14; Protein phosphatase that negatively regulates the G1-to-S phase transition to inhibit the cell cycle and establish quiescence in cells of multiple lineages including vulval, hypodermal and intestinal. Promotes nuclear accumulation and activity of the cyclin-dependent kinase inhibitor cki-1 which leads to inhibition of G1 progression during vulval tissue development. Has been shown to not be required for cytokinesis. However, in the embryo, in a contrasting study, has been shown to act as a regulator of central spindle formation and cytokinesis, and [...]
    
 
 0.521
T12B3.1
TYR_PHOSPHATASE_2 domain-containing protein.
    
 
 0.521
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.