STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cox-17Cytochrome OXidase assembly protein. (63 aa)    
Predicted Functional Partners:
cox-11
Cytochrome OXidase assembly protein.
   
  
 0.990
cuc-1
HMA domain-containing protein.
   
 
 0.939
puf-3
PUM-HD domain-containing protein.
    
 
 0.888
tin-10
Mitochondrial import inner membrane translocase subunit Tim10; Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (Probable).
   
  
 0.853
cox-15
Cytochrome OXidase assembly protein.
   
  
 0.843
cox-10
Protoheme IX farnesyltransferase, mitochondrial; Converts protoheme IX and farnesyl diphosphate to heme O. Belongs to the ubiA prenyltransferase family.
      
 0.842
cox-6B
Cytochrome OXidase assembly protein.
   
  
 0.824
coa-5
Cytochrome Oxidase Assembly subunits.
   
  
 0.823
cox-18
Cytochrome OXidase assembly protein.
   
  
 0.811
sco-1
SCO (Yeast Suppressor of Cytochrome Oxidase deficiency) homolog.
   
 
 0.809
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.