STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glr-6PBPe domain-containing protein. (844 aa)    
Predicted Functional Partners:
srh-18
Serpentine Receptor, class H.
      
 0.660
dlg-1
Disks large homolog 1; Essential multidomain scaffolding protein required for normal development (Probable). Recruits channels, receptors and signaling molecules to discrete plasma membrane domains in polarized cells (By similarity). Required for proper embryonic elongation. Acts upstream of ajm-1 and becomes localized to apical junctions independently of ajm-1. With let-413, cooperatively regulates ajm-1 localization to apical junctions. Belongs to the MAGUK family.
   
 0.626
eat-4
Probable vesicular glutamate transporter eat-4; Required for glutamatergic synaptic transmission. In AWB and AWC sensory neurons, required for the detection of preferred food sources, probably via glutamatergic neurotransmission from sensory neurons. Negatively regulates the turning step of male mating behavior.
   
  
 0.621
vglu-3
Potential vesicular glutamate transporter vglu-3.
      
 0.612
glr-3
GLutamate Receptor family (AMPA).
  
  
0.581
aat-1
Amino Acid Transporter.
   
  
 0.566
glr-4
GLutamate Receptor family (AMPA).
  
 
0.557
swip-10
Lactamase_B domain-containing protein.
   
  
 0.533
cal-2
CALmodulin related genes.
   
 
 0.518
ncs-2
Neuronal calcium sensor 2; Neuronal calcium sensor, regulator of G protein-coupled receptor phosphorylation in a calcium dependent manner; Belongs to the recoverin family.
   
 
  0.508
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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