STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
agr-1AGRin (Synaptic protein) homolog family member. (1473 aa)    
Predicted Functional Partners:
dgn-1
Peptidase S72 domain-containing protein.
   
 0.968
rpy-1
43 kDa receptor-associated protein of the synapse homolog; Postsynaptic protein required for clustering of nicotinic acetylcholine receptors (nAChRs) at the neuromuscular junction.
   
  
 0.940
cle-1
CoLlagen with Endostatin domain.
   
 
 0.859
sdn-1
Probable syndecan; Cell surface proteoglycan that bears heparan sulfate (By similarity). Required for correct mitotic spindle orientation of the ABar blastomere division plane and this may be through modulation of astral microtubule array, and in association with the wnt-signaling proteins mig-5 and dsh-2. Involved in the migration of AQR and PQR neurons, which descend from the Q neuroblasts. Promotes the axon guidance of D-type motor neurons.
   
  
 0.851
gpn-1
GlyPicaN; Belongs to the glypican family.
      
 0.845
lrp-1
Low-density lipoprotein receptor-related protein; May act as a receptor for the endocytosis of extracellular ligands such as chylomicron remnants, protease-inhibitor complexes and vitellogenin; Belongs to the LDLR family.
   
 
 0.798
bgnt-1.4
B3GNT1, Beta-1,3-N-acetylGucosamiNylTransferase 1, homolog.
   
 
 0.773
bgnt-1.5
B3GNT1, Beta-1,3-N-acetylGucosamiNylTransferase 1, homolog.
   
 
 0.773
nid-1
NIDogen (Basement membrane protein).
   
 
 0.760
lrp-2
Low-density lipoprotein RecePtor related.
   
 
 0.734
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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