node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cct-7 | pfd-1 | T10B5.5a.2 | C08F8.1a.1 | T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. | Probable prefoldin subunit 1; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins (By similarity). Has a role in gonadogenesis; Belongs to the prefoldin subunit beta family. | 0.800 |
cct-7 | ppm-1.G | T10B5.5a.2 | F42G9.1a.1 | T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. | Protein phosphatase ppm-1.G; Belongs to the PP2C family. | 0.493 |
hmp-1 | ppm-1.G | R13H4.4b.1 | F42G9.1a.1 | Alpha-catenin-like protein hmp-1; Required for cell migration during body enclosure and cell shape changes during body elongation. Required for proper localization of other junctional components, such as pac-1 ; Belongs to the vinculin/alpha-catenin family. | Protein phosphatase ppm-1.G; Belongs to the PP2C family. | 0.522 |
kin-15 | kin-16 | M176.6a.1 | M176.7.1 | Receptor-like tyrosine-protein kinase kin-15; May be specifically involved in cell-cell interactions regulating cell fusions that generate the hypodermis during postembryonic development. It has a role in the development of the HYP7 hypodermal syncytium. | Receptor-like tyrosine-protein kinase kin-16; May be specifically involved in cell-cell interactions regulating cell fusions that generate the hypodermis during postembryonic development. It has a role in the development of the HYP7 hypodermal syncytium. | 0.593 |
kin-15 | ppm-1.G | M176.6a.1 | F42G9.1a.1 | Receptor-like tyrosine-protein kinase kin-15; May be specifically involved in cell-cell interactions regulating cell fusions that generate the hypodermis during postembryonic development. It has a role in the development of the HYP7 hypodermal syncytium. | Protein phosphatase ppm-1.G; Belongs to the PP2C family. | 0.696 |
kin-16 | kin-15 | M176.7.1 | M176.6a.1 | Receptor-like tyrosine-protein kinase kin-16; May be specifically involved in cell-cell interactions regulating cell fusions that generate the hypodermis during postembryonic development. It has a role in the development of the HYP7 hypodermal syncytium. | Receptor-like tyrosine-protein kinase kin-15; May be specifically involved in cell-cell interactions regulating cell fusions that generate the hypodermis during postembryonic development. It has a role in the development of the HYP7 hypodermal syncytium. | 0.593 |
kin-16 | ppm-1.G | M176.7.1 | F42G9.1a.1 | Receptor-like tyrosine-protein kinase kin-16; May be specifically involved in cell-cell interactions regulating cell fusions that generate the hypodermis during postembryonic development. It has a role in the development of the HYP7 hypodermal syncytium. | Protein phosphatase ppm-1.G; Belongs to the PP2C family. | 0.674 |
math-33 | ppm-1.G | H19N07.2k.1 | F42G9.1a.1 | Ubiquitin carboxyl-terminal hydrolase 7; Hydrolase that deubiquitinates target proteins. | Protein phosphatase ppm-1.G; Belongs to the PP2C family. | 0.589 |
math-33 | sig-7 | H19N07.2k.1 | F39H2.2a.2 | Ubiquitin carboxyl-terminal hydrolase 7; Hydrolase that deubiquitinates target proteins. | Peptidyl-prolyl cis-trans isomerase sig-7; Probable PPIase that accelerates the folding of proteins (By similarity). It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity). Involved in RNA polymerase II (RNA pol II)-mediated transcription elongation, and in primary transcript splicing, including co-transcriptional trans- splicing, in association with the catalytic subunit of the RNA pol II complex ama-1. Also plays a role in the regulation of elongation-dependent phosphorylation of ama-1 to control transcription. Involved in the transc [...] | 0.414 |
pfd-1 | cct-7 | C08F8.1a.1 | T10B5.5a.2 | Probable prefoldin subunit 1; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins (By similarity). Has a role in gonadogenesis; Belongs to the prefoldin subunit beta family. | T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. | 0.800 |
pfd-1 | ppm-1.G | C08F8.1a.1 | F42G9.1a.1 | Probable prefoldin subunit 1; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins (By similarity). Has a role in gonadogenesis; Belongs to the prefoldin subunit beta family. | Protein phosphatase ppm-1.G; Belongs to the PP2C family. | 0.665 |
pfd-1 | repo-1 | C08F8.1a.1 | F11A10.2.1 | Probable prefoldin subunit 1; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins (By similarity). Has a role in gonadogenesis; Belongs to the prefoldin subunit beta family. | Matrin-type domain-containing protein. | 0.408 |
pph-6 | ppm-1.G | C34C12.3.1 | F42G9.1a.1 | Serine/threonine-protein phosphatase 6 catalytic subunit; Catalytic subunit of protein phosphatase 6 (PP6) (By similarity). In complex with saps-1, promotes actomyosin contractility during cytokinesis by regulating the organization of cortical non- muscle myosin II nmy-2 and thus contributing to correct spindle positioning. Also required for the proper generation of pulling forces on spindle poles during anaphase by regulating the cortical localization of gpr-1, gpr-2 and lin-5. Belongs to the PPP phosphatase family. PP-6 (PP-V) subfamily. | Protein phosphatase ppm-1.G; Belongs to the PP2C family. | 0.528 |
ppm-1.G | cct-7 | F42G9.1a.1 | T10B5.5a.2 | Protein phosphatase ppm-1.G; Belongs to the PP2C family. | T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. | 0.493 |
ppm-1.G | hmp-1 | F42G9.1a.1 | R13H4.4b.1 | Protein phosphatase ppm-1.G; Belongs to the PP2C family. | Alpha-catenin-like protein hmp-1; Required for cell migration during body enclosure and cell shape changes during body elongation. Required for proper localization of other junctional components, such as pac-1 ; Belongs to the vinculin/alpha-catenin family. | 0.522 |
ppm-1.G | kin-15 | F42G9.1a.1 | M176.6a.1 | Protein phosphatase ppm-1.G; Belongs to the PP2C family. | Receptor-like tyrosine-protein kinase kin-15; May be specifically involved in cell-cell interactions regulating cell fusions that generate the hypodermis during postembryonic development. It has a role in the development of the HYP7 hypodermal syncytium. | 0.696 |
ppm-1.G | kin-16 | F42G9.1a.1 | M176.7.1 | Protein phosphatase ppm-1.G; Belongs to the PP2C family. | Receptor-like tyrosine-protein kinase kin-16; May be specifically involved in cell-cell interactions regulating cell fusions that generate the hypodermis during postembryonic development. It has a role in the development of the HYP7 hypodermal syncytium. | 0.674 |
ppm-1.G | math-33 | F42G9.1a.1 | H19N07.2k.1 | Protein phosphatase ppm-1.G; Belongs to the PP2C family. | Ubiquitin carboxyl-terminal hydrolase 7; Hydrolase that deubiquitinates target proteins. | 0.589 |
ppm-1.G | pfd-1 | F42G9.1a.1 | C08F8.1a.1 | Protein phosphatase ppm-1.G; Belongs to the PP2C family. | Probable prefoldin subunit 1; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins (By similarity). Has a role in gonadogenesis; Belongs to the prefoldin subunit beta family. | 0.665 |
ppm-1.G | pph-6 | F42G9.1a.1 | C34C12.3.1 | Protein phosphatase ppm-1.G; Belongs to the PP2C family. | Serine/threonine-protein phosphatase 6 catalytic subunit; Catalytic subunit of protein phosphatase 6 (PP6) (By similarity). In complex with saps-1, promotes actomyosin contractility during cytokinesis by regulating the organization of cortical non- muscle myosin II nmy-2 and thus contributing to correct spindle positioning. Also required for the proper generation of pulling forces on spindle poles during anaphase by regulating the cortical localization of gpr-1, gpr-2 and lin-5. Belongs to the PPP phosphatase family. PP-6 (PP-V) subfamily. | 0.528 |