STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cpn-1Calponin-homology (CH) domain-containing protein. (192 aa)    
Predicted Functional Partners:
B0261.7
Uncharacterized protein.
   
  
 0.711
C39E9.12
SAP domain-containing protein.
   
 
 0.690
pcrg-1
Parkin Co-Regulated Gene (PACRG) homolog.
    
 
 0.689
C54C6.6
Cilia- and flagella-associated protein 20; Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility; Belongs to the CFAP20 family.
   
 
 0.685
efhc-1
EF-Hand domain-Containing protein 1 homolog.
   
 
 0.684
K06H6.2
Methyltransf_21 domain-containing protein.
    
 
 0.668
chdp-1
Calponin-homology (CH) domain-containing protein.
   
  
 0.667
act-5
ACTin.
   
 
 0.642
C48B4.11
Uncharacterized protein C48B4.11.
   
  
 0.639
pfn-1
Profilin-1; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Also binds to poly(L-proline) and phosphatidylinositol 4,5-bisphosphate micelles.
   
 
 0.636
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.