node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ceh-14 | ceh-17 | F46C8.5.1 | D1007.1.1 | Homeobox protein ceh-14; Confers thermosensory function to neurons. Required for correct AFD-mediated thermotaxis. | Homeobox domain-containing protein. | 0.825 |
ceh-14 | ceh-43 | F46C8.5.1 | C28A5.4b.1 | Homeobox protein ceh-14; Confers thermosensory function to neurons. Required for correct AFD-mediated thermotaxis. | Homeobox protein ceh-43; Required for development of the anterior hypdermis during embryonic morphogenesis for cell adhesion; also affects embryonic and larval viability. | 0.696 |
ceh-14 | cfi-1 | F46C8.5.1 | T23D8.8.1 | Homeobox protein ceh-14; Confers thermosensory function to neurons. Required for correct AFD-mediated thermotaxis. | AT-rich interactive domain-containing protein cfi-1; Transcription factor which regulates neuronal subtype identity. Promotes differentiation of URA sensory neurons and prevents them to express male-specific CEM features. Promotes differentiation of AVD and PVC interneurons and their glutamate receptor expression. | 0.681 |
ceh-14 | ldb-1 | F46C8.5.1 | F58A3.1c.1 | Homeobox protein ceh-14; Confers thermosensory function to neurons. Required for correct AFD-mediated thermotaxis. | LID domain-containing protein. | 0.842 |
ceh-14 | lim-7 | F46C8.5.1 | C04F1.3.1 | Homeobox protein ceh-14; Confers thermosensory function to neurons. Required for correct AFD-mediated thermotaxis. | LIM domain family. | 0.948 |
ceh-14 | sam-10 | F46C8.5.1 | Y48C3A.8a.1 | Homeobox protein ceh-14; Confers thermosensory function to neurons. Required for correct AFD-mediated thermotaxis. | Single-stranded DNA-binding protein homolog sam-10; Involved cell autonomously in PLM neuron pre-synaptic differentiation by negatively regulating prk-2 expression and in neurite branch positioning. | 0.674 |
ceh-14 | ttx-1 | F46C8.5.1 | Y113G7A.6a.1 | Homeobox protein ceh-14; Confers thermosensory function to neurons. Required for correct AFD-mediated thermotaxis. | Homeobox domain-containing protein. | 0.843 |
ceh-14 | unc-3 | F46C8.5.1 | Y16B4A.1.1 | Homeobox protein ceh-14; Confers thermosensory function to neurons. Required for correct AFD-mediated thermotaxis. | Transcription factor unc-3; May play a role in the expression of proteins essential for axonal pathfinding and/or neuronal differentiation in both sensory and motor neurons. Cooperates with jmjd-3.1 and wdr-5.1 to ensure robust transdifferentiation of the Y rectal cell to the PDA motor neuron during larval development. | 0.703 |
ceh-14 | unc-30 | F46C8.5.1 | B0564.10b.1 | Homeobox protein ceh-14; Confers thermosensory function to neurons. Required for correct AFD-mediated thermotaxis. | Homeobox protein unc-30; Transcriptional regulator within D-type neurons that controls terminal differentiation. Required for the development and function of the 19 inhibitory GABAergic (gamma-aminobutyric-acid- secreting) D-type motor neurons, which control locomotion. Plays a role in regulating synapse formation in dorsal D (DD) and ventral D (VD) GABAergic motor neurons, possibly in part by regulating the expression of the neural regulator oig-1. Also required for expression of flp-13 in DD motor neurons. Plays a role in respecification of DD motor neurons through regulation of gene [...] | 0.707 |
ceh-14 | unc-86 | F46C8.5.1 | C30A5.7b.1 | Homeobox protein ceh-14; Confers thermosensory function to neurons. Required for correct AFD-mediated thermotaxis. | Transcription factor unc-86; Transcription factor required for correct cell fate determination and differentiation in diverse neuronal cell lineages where it plays a role in specifying the fate of daughter cells during cell divisions. Involved in sensory neuron production and function. Binds both alone and with mec-3 to the mec-3 promoter to initiate and maintain mec-3 expression which is required for sensory neuron differentiation. In addition, binds both alone and with mec-3 to the promoters of mec-4 and mec-7 which act to regulate sensory neuron function. Involved in determining the [...] | 0.811 |
ceh-17 | ceh-14 | D1007.1.1 | F46C8.5.1 | Homeobox domain-containing protein. | Homeobox protein ceh-14; Confers thermosensory function to neurons. Required for correct AFD-mediated thermotaxis. | 0.825 |
ceh-17 | unc-86 | D1007.1.1 | C30A5.7b.1 | Homeobox domain-containing protein. | Transcription factor unc-86; Transcription factor required for correct cell fate determination and differentiation in diverse neuronal cell lineages where it plays a role in specifying the fate of daughter cells during cell divisions. Involved in sensory neuron production and function. Binds both alone and with mec-3 to the mec-3 promoter to initiate and maintain mec-3 expression which is required for sensory neuron differentiation. In addition, binds both alone and with mec-3 to the promoters of mec-4 and mec-7 which act to regulate sensory neuron function. Involved in determining the [...] | 0.402 |
ceh-43 | ceh-14 | C28A5.4b.1 | F46C8.5.1 | Homeobox protein ceh-43; Required for development of the anterior hypdermis during embryonic morphogenesis for cell adhesion; also affects embryonic and larval viability. | Homeobox protein ceh-14; Confers thermosensory function to neurons. Required for correct AFD-mediated thermotaxis. | 0.696 |
ceh-43 | lim-7 | C28A5.4b.1 | C04F1.3.1 | Homeobox protein ceh-43; Required for development of the anterior hypdermis during embryonic morphogenesis for cell adhesion; also affects embryonic and larval viability. | LIM domain family. | 0.503 |
ceh-43 | unc-3 | C28A5.4b.1 | Y16B4A.1.1 | Homeobox protein ceh-43; Required for development of the anterior hypdermis during embryonic morphogenesis for cell adhesion; also affects embryonic and larval viability. | Transcription factor unc-3; May play a role in the expression of proteins essential for axonal pathfinding and/or neuronal differentiation in both sensory and motor neurons. Cooperates with jmjd-3.1 and wdr-5.1 to ensure robust transdifferentiation of the Y rectal cell to the PDA motor neuron during larval development. | 0.494 |
ceh-43 | unc-86 | C28A5.4b.1 | C30A5.7b.1 | Homeobox protein ceh-43; Required for development of the anterior hypdermis during embryonic morphogenesis for cell adhesion; also affects embryonic and larval viability. | Transcription factor unc-86; Transcription factor required for correct cell fate determination and differentiation in diverse neuronal cell lineages where it plays a role in specifying the fate of daughter cells during cell divisions. Involved in sensory neuron production and function. Binds both alone and with mec-3 to the mec-3 promoter to initiate and maintain mec-3 expression which is required for sensory neuron differentiation. In addition, binds both alone and with mec-3 to the promoters of mec-4 and mec-7 which act to regulate sensory neuron function. Involved in determining the [...] | 0.722 |
cfi-1 | ceh-14 | T23D8.8.1 | F46C8.5.1 | AT-rich interactive domain-containing protein cfi-1; Transcription factor which regulates neuronal subtype identity. Promotes differentiation of URA sensory neurons and prevents them to express male-specific CEM features. Promotes differentiation of AVD and PVC interneurons and their glutamate receptor expression. | Homeobox protein ceh-14; Confers thermosensory function to neurons. Required for correct AFD-mediated thermotaxis. | 0.681 |
cfi-1 | unc-3 | T23D8.8.1 | Y16B4A.1.1 | AT-rich interactive domain-containing protein cfi-1; Transcription factor which regulates neuronal subtype identity. Promotes differentiation of URA sensory neurons and prevents them to express male-specific CEM features. Promotes differentiation of AVD and PVC interneurons and their glutamate receptor expression. | Transcription factor unc-3; May play a role in the expression of proteins essential for axonal pathfinding and/or neuronal differentiation in both sensory and motor neurons. Cooperates with jmjd-3.1 and wdr-5.1 to ensure robust transdifferentiation of the Y rectal cell to the PDA motor neuron during larval development. | 0.817 |
cfi-1 | unc-86 | T23D8.8.1 | C30A5.7b.1 | AT-rich interactive domain-containing protein cfi-1; Transcription factor which regulates neuronal subtype identity. Promotes differentiation of URA sensory neurons and prevents them to express male-specific CEM features. Promotes differentiation of AVD and PVC interneurons and their glutamate receptor expression. | Transcription factor unc-86; Transcription factor required for correct cell fate determination and differentiation in diverse neuronal cell lineages where it plays a role in specifying the fate of daughter cells during cell divisions. Involved in sensory neuron production and function. Binds both alone and with mec-3 to the mec-3 promoter to initiate and maintain mec-3 expression which is required for sensory neuron differentiation. In addition, binds both alone and with mec-3 to the promoters of mec-4 and mec-7 which act to regulate sensory neuron function. Involved in determining the [...] | 0.753 |
ldb-1 | ceh-14 | F58A3.1c.1 | F46C8.5.1 | LID domain-containing protein. | Homeobox protein ceh-14; Confers thermosensory function to neurons. Required for correct AFD-mediated thermotaxis. | 0.842 |