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ceh-14 protein (Caenorhabditis elegans) - STRING interaction network
"ceh-14" - Homeobox protein ceh-14 in Caenorhabditis elegans
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurence
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[Homology]
Score
ceh-14Homeobox protein ceh-14; Confers thermosensory function to neurons. Required for correct AFD-mediated thermotaxis (351 aa)    
Predicted Functional Partners:
lim-7
LIM domain family; Protein LIM-7 (lim-7) mRNA, complete cds (452 aa)
     
 
0.919
unc-86
Transcription factor unc-86; Transcription factor required for correct cell fate determination and differentiation in diverse neuronal cell lineages where it plays a role in specifying the fate of daughter cells during cell divisions. Involved in sensory neuron production and function. Binds both alone and with mec-3 to the mec-3 promoter to initiate and maintain mec-3 expression which is required for sensory neuron differentiation. In addition, binds both alone and with mec-3 to the promoters of mec-4 and mec- 7 which act to regulate sensory neuron function. Involved in determining th [...] (357 aa)
     
 
  0.896
col-43
Collagen; Protein COL-43 (col-43) mRNA, complete cds (303 aa)
           
  0.799
ldb-1
LIM Domain Binding protein; Protein LDB-1, isoform c (629 aa)
       
 
  0.795
cog-1
COG-1A; Protein COG-1, isoform a (256 aa)
       
 
  0.745
ttx-1
Protein TTX-1, isoform a (391 aa)
           
  0.740
ceh-17
C. Elegans Homeobox; Protein CEH-17 (ceh-17) mRNA, complete cds (237 aa)
     
   
  0.734
ceh-30
Homeobox protein ceh-30; Cell-type specific anti-apoptotic transcription factor required for the sexually dimorphic survival of the male-specific CEM (cephalic male) sensory neurons during sex determination. In hermaphrodites, the homologous cells undergo programmed cell death due to transcriptional repression of ceh-30 by tra-1, the terminal regulator in the sex determination pathway (237 aa)
           
  0.711
B0507.3
Protein B0507.3, isoform a (432 aa)
       
      0.705
cnd-1
Neurogenic differentiation factor 1; Acts as a transcriptional regulator whose activity is required for several aspects of motor neuron fate specification, including cell division patterns, proper spatiotemporal expression of fate-specific markers, and normal axonal morphology and pathfinding (192 aa)
     
   
  0.681
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Caenorhabditis elegans, Rhabditis elegans, roundworm
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