STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sra-13Serpentine receptor class alpha-13; Chemosensory receptor that negatively regulates RAS/MAPK signaling during vulva induction and the negative regulation of olfaction of volitile attractants. Required for the suppression of vulval induction in response to food starvation. Signaling acts through the GPA-5 G-alpha protein subunit; Belongs to the nematode receptor-like protein sra family. (335 aa)    
Predicted Functional Partners:
srsx-5
G_PROTEIN_RECEP_F1_2 domain-containing protein.
   
  
 0.812
str-130
Seven TM Receptor.
      
 0.810
str-199
Seven TM Receptor.
      
 0.810
sri-14
Serpentine Receptor, class I.
      
 0.807
srd-5
Serpentine Receptor, class D (Delta).
   
  
 0.707
srj-22
Serpentine Receptor, class J.
   
  
 0.706
srj-21
Serpentine Receptor, class J.
   
  
 0.703
srt-29
Serpentine Receptor, class T.
      
 0.700
srt-7
Serpentine Receptor, class T.
      
 0.699
gpa-5
Guanine nucleotide-binding protein alpha-5 subunit; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems; Belongs to the G-alpha family.
      
 0.698
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
Server load: medium (80%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.