STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rpl-25.260S ribosomal protein L23a 2; This protein binds to a specific region on the 26S rRNA. (146 aa)    
Predicted Functional Partners:
rps-3
40S ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family.
  
 
 0.999
rps-30
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
   
 
 0.999
rpl-5
60S ribosomal protein L5; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...]
  
 
 0.999
rpl-23
60S ribosomal protein L23; Belongs to the universal ribosomal protein uL14 family.
  
 
 0.998
rps-0
40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.
  
 
 0.998
rps-13
40S ribosomal protein S13; Belongs to the universal ribosomal protein uS15 family.
  
 
 0.998
rpl-27
60S ribosomal protein L27; Component of the large ribosomal subunit.
  
 
 0.998
rpl-33
60S ribosomal protein L35a; Belongs to the eukaryotic ribosomal protein eL33 family.
   
 
 0.998
rps-15
40S ribosomal protein S15; Negatively regulates lifespan.
  
 
 0.998
rps-14
40S ribosomal protein S14; Belongs to the universal ribosomal protein uS11 family.
  
 
 0.998
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.