STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F52H2.6Diminuto-like protein; Belongs to the DIMINUTO family. (525 aa)    
Predicted Functional Partners:
dhcr-7
DeHydroCholesterol Reductase.
   
 
 0.990
Y7A5A.1
FAD-binding PCMH-type domain-containing protein.
  
 
0.923
mboa-1
O-acyltransferase.
   
 
 0.911
lipl-5
Lipase; Belongs to the AB hydrolase superfamily. Lipase family.
   
 
 0.906
lipl-1
Lipase; Belongs to the AB hydrolase superfamily. Lipase family.
     
 0.903
idi-1
Nudix hydrolase domain-containing protein.
  
  
 0.895
hmgr-1
3-hydroxy-3-methylglutaryl coenzyme A reductase.
   
  
 0.814
F54D5.12
FAD-binding PCMH-type domain-containing protein.
      
 0.807
icl-1
Bifunctional glyoxylate cycle protein; In the C-terminal section; belongs to the malate synthase family.
  
 
 0.794
erg-28
Probable ergosterol biosynthetic protein 28 homolog; Promotes the translocation of slo-1 potassium ion channels from the endoplasmic reticulum to its final destination at the plasma membrane, probably by shielding from premature proteasomal degradation in the endoplasmic reticulum; Belongs to the ERG28 family.
   
  
 0.783
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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