STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
jbts-14Transmembrane protein 237 homolog; Component of the transition zone in primary cilia. Required for ciliogenesis; Belongs to the TMEM237 family. (399 aa)    
Predicted Functional Partners:
tmem-231
TMEM (Human TransMEMbrane protein) homolog.
   
  
 0.990
tmem-17
TMEM (Human TransMEMbrane protein) homolog.
   
  
 0.975
nphp-1
Nephrocystin-1-like protein; May be necessary for initial assembly of the cilium.
   
 
 0.954
nphp-4
NePHronoPhthisis (Human kidney disease) homolog.
   
  
 0.939
mks-1
MecKel-Gruber Syndrome (MKS) homolog.
   
  
 0.899
mksr-1
MecKel Syndrome 1 (MKS1)-Related.
   
  
 0.891
mksr-2
MecKel Syndrome 1 (MKS1)-Related.
   
  
 0.864
tmem-138
TMEM (Human TransMEMbrane protein) homolog.
   
 
 0.851
mks-6
C2 domain-containing protein.
   
  
 0.837
mks-5
Protein fantom; Thought to have an important role in cilia formation and cilia-mediated chemosensation. Involved in the docking of other MKS/MKSR proteins localized to the transition zone of the cilia. Belongs to the RPGRIP1 family.
   
 
 0.810
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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