STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
swip-10Lactamase_B domain-containing protein. (421 aa)    
Predicted Functional Partners:
dop-3
Dopamine receptor 3; Receptor for dopamine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. In terms of antagonist responses, would be classed with the D2-like dopamine receptor group. Mediates the effect of dopamine on the inhibition of locomotion. Acts as an antagonist of dop-1.
   
  
 0.851
gei-13
Gex-3-interacting protein 13.
   
  
 0.841
dat-1
Sodium-dependent dopamine transporter; Dopamine transporter. Terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals.
      
 0.810
C54G6.2
C-CAP/cofactor C-like domain-containing protein.
      
 0.809
C54G6.3
Uncharacterized protein.
      
 0.807
aat-7
Amino Acid Transporter.
      
 0.741
aat-1
Amino Acid Transporter.
   
  
 0.720
vglu-3
Potential vesicular glutamate transporter vglu-3.
      
 0.699
clp-1
Calpain clp-1; Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates (By similarity). Required for assembly and maintenance of integrin attachment complexes which are essential for maintenance of adult muscle. Proteolytic activity is activated in response to increased intracellular Ca(2+) levels during cell degeneration and promotes necrotic cell death.
      
 0.660
aat-6
Amino acid transporter protein 6; Amino acid transporter that mediates the uptake of the L- enantiomers of various amino acids, including L-glutamate (Probable). May play a role in promoting fertility.
      
 0.660
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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