STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F53B3.5Uncharacterized protein. (312 aa)    
Predicted Functional Partners:
ZK1290.11
Uncharacterized protein ZK1290.11.
      
 0.904
stg-1
STarGazin (Mammalian calcium channel) homolog.
      
 0.803
wrt-1
Warthog protein 1 C-product; Intercellular signal essential for a variety of patterning events during development.
   
  
 0.704
sol-1
Suppressor of lurcher protein 1; Accessory protein required for glutamate-gated currents. May participate in the gating of non-NMDA (N-methyl-D-aspartate) ionotropic glutamate receptors such as glr-1.
      
 0.668
alh-9
Putative aldehyde dehydrogenase family 7 member A1 homolog; Belongs to the aldehyde dehydrogenase family.
      
 0.667
wrt-4
Warthog protein 4 C-product; Intercellular signal essential for a variety of patterning events during development.
      
 0.663
wrt-2
WaRThog (Hedgehog-like family).
   
  
 0.567
dpy-8
Col_cuticle_N domain-containing protein.
   
  
 0.541
dpy-2
Cuticle collagen dpy-2; Nematode cuticles are composed largely of collagen-like proteins. The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment. Mutations in dpy-2 affects the body shape.
   
  
 0.509
dpy-3
Col_cuticle_N domain-containing protein.
   
  
 0.493
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.