STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
twk-32TWiK family of potassium channels; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (614 aa)    
Predicted Functional Partners:
twk-14
TWiK family of potassium channels; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
   
 
0.689
twk-20
Two pore potassium channel protein sup-9.
   
 
0.675
sup-9
Two pore potassium channel protein sup-9; Potassium channel involved in coordination of muscle contraction. Activity is regulated by sup-18 ; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
   
 
0.667
twk-46
Two pore potassium channel protein sup-9.
     
0.652
twk-6
TWiK family of potassium channels; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
   
 
0.631
twk-29
TWiK family of potassium channels; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
     
0.627
twk-17
Putative potassium channel subunit n2P17m2-2; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
     
0.606
twk-47
Ion_trans_2 domain-containing protein.
     
0.605
twk-16
TWiK family of potassium channels; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
     
0.599
twk-3
TWiK family of potassium channels; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
   
 
0.592
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
Server load: medium (78%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.