STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
apm-3MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. (414 aa)    
Predicted Functional Partners:
apb-3
AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family.
   
 0.999
apd-3
AP-3 complex subunit delta; Belongs to the adaptor complexes large subunit family.
   
 0.999
aps-3
Clat_adaptor_s domain-containing protein.
   
 0.997
apg-1
AP-1 complex subunit gamma.
   
 0.847
apa-2
AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
   
 0.791
hhat-2
Homolog of Hedgehog AcylTransferase; Belongs to the membrane-bound acyltransferase family.
      
 0.759
acp-5
ACid Phosphatase family; Belongs to the histidine acid phosphatase family.
      
 0.741
glo-1
Gut granule LOss.
   
 
 0.725
glo-4
X-linked retinitis pigmentosa GTPase regulator homolog; Could be a guanine-nucleotide releasing factor for glo-1. May play a role in gut granule biogenesis. Regulates axon termination in PLM and ALM neurons.
      
 0.700
T19D2.2
Putative prenylated protein tyrosine phosphatase.
      
 0.700
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.