STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F54C8.7Uncharacterized protein F54C8.7. (307 aa)    
Predicted Functional Partners:
arl-1
ADP-ribosylation factor-like protein 1; GTP-binding protein that may be involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus. Plays a role in male tail tip morphogenesis.
   
 0.960
ric-19
Resistance to inhibitors of cholinesterase protein 19; May be involved in a role in neurotransmitter secretion.
      
 0.743
arf-6
ADP-Ribosylation Factor related; Belongs to the small GTPase superfamily. Arf family.
    
 
 0.720
amph-1
AMPHiphysin homolog.
      
 0.559
H10E21.5
RING-type domain-containing protein.
   
  
 0.542
M01F1.3
Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives; Belongs to the radical SAM superfamily. Lipoyl synthase family.
   
  
 0.517
sbt-1
Seven B Two (Mammalian 7BT prohormone convertase chaperone) homolog.
      
 0.461
arf-1.2
ADP-ribosylation factor 1-like 2; GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus. Involved in endoplasmic reticulum dynamics during embryogenesis. Also required for adult germline function. Plays a role in cell shedding during embryogenesis probably by promoting the endocytosis of cell adhesion molecules. During neurogenesis, involved in cell autonomous Q.p neuroblast asymmetric divisions that generate one precursor cell and one apoptotic cell, probably by controlling endocytosis.
   
 
 0.437
golg-2
GOLGi associated coiled-coil protein homolog.
   
  
 0.433
eas-1
Probable Golgi transport protein 1; May be involved in fusion of ER-derived transport vesicles with the Golgi complex; Belongs to the GOT1 family.
   
    0.401
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
Server load: low (38%) [HD]