STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pmt-2Phosphoethanolamine MethylTransferase. (437 aa)    
Predicted Functional Partners:
pmt-1
Methyltransf_11 domain-containing protein.
 
  
 0.991
pcyt-1
Putative choline-phosphate cytidylyltransferase; Belongs to the cytidylyltransferase family.
  
 
 0.990
ckb-1
Choline kinase B1; Belongs to the choline/ethanolamine kinase family.
  
 
 0.973
ckc-1
Choline Kinase C.
  
 
 0.967
W08F4.3
Uncharacterized protein.
   
 0.952
cka-2
Choline kinase A2; Catalyzes the first step in phosphatidylcholine biosynthesis. May contribute to phosphatidylethanolamine biosynthesis. Phosphorylates choline and ethanolamine but the activity is much higher with choline. Belongs to the choline/ethanolamine kinase family.
  
 
 0.941
eppl-1
Ethanolamine-phosphate phospho-lyase homolog 1.
   
 
 0.937
dhcr-7
DeHydroCholesterol Reductase.
   
 
 0.936
ckb-2
Choline kinase B2; Catalyzes the first step in phosphatidylcholine biosynthesis. Phosphorylates choline.
    
 0.931
pcyt-2.2
CTP_transf_like domain-containing protein.
  
 
 0.927
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.