node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
eme-1 | ercc-1 | F56A6.4a.1 | F10G8.7.2 | Essential Meiotic Endonuclease. | ERCC (DNA excision repair protein) homolog. | 0.788 |
eme-1 | gen-1 | F56A6.4a.1 | T12A2.8.2 | Essential Meiotic Endonuclease. | GEN1 Holliday junction resolvase homolog. | 0.806 |
eme-1 | him-18 | F56A6.4a.1 | T04A8.15.1 | Essential Meiotic Endonuclease. | High Incidence of Males (Increased X chromosome loss). | 0.791 |
eme-1 | mus-81 | F56A6.4a.1 | C43E11.2a.1 | Essential Meiotic Endonuclease. | ERCC4 domain-containing protein. | 0.959 |
eme-1 | polh-1 | F56A6.4a.1 | F53A3.2.1 | Essential Meiotic Endonuclease. | UmuC domain-containing protein. | 0.414 |
eme-1 | slx-1 | F56A6.4a.1 | F56A3.2.1 | Essential Meiotic Endonuclease. | Structure-specific endonuclease subunit SLX1 homolog; Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA (Potential). Has a preference for replication forks over 5' flap structures or Holliday junctions and shows much lower activity toward 3' flap structures. Required for proper crossover distribution through inhibition of crossover formation at the c [...] | 0.806 |
eme-1 | smo-1 | F56A6.4a.1 | K12C11.2.1 | Essential Meiotic Endonuclease. | Small ubiquitin-related modifier; Ubiquitin-like protein which can be covalently attached to target lysines as a monomer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex aos-1-uba-2 and linkage to the E2 enzyme ubc-9, and can be promoted by an E3 ligase such as gei-17. Required for embryonic dev [...] | 0.409 |
eme-1 | trp-1 | F56A6.4a.1 | ZC21.2b.1 | Essential Meiotic Endonuclease. | Transient-receptor-potential-like protein; Could mediate calcium entry and form a calcium permeant channel; Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. | 0.418 |
eme-1 | xpf-1 | F56A6.4a.1 | C47D12.8.1 | Essential Meiotic Endonuclease. | ERCC4 domain-containing protein. | 0.775 |
ercc-1 | eme-1 | F10G8.7.2 | F56A6.4a.1 | ERCC (DNA excision repair protein) homolog. | Essential Meiotic Endonuclease. | 0.788 |
ercc-1 | gen-1 | F10G8.7.2 | T12A2.8.2 | ERCC (DNA excision repair protein) homolog. | GEN1 Holliday junction resolvase homolog. | 0.927 |
ercc-1 | him-18 | F10G8.7.2 | T04A8.15.1 | ERCC (DNA excision repair protein) homolog. | High Incidence of Males (Increased X chromosome loss). | 0.964 |
ercc-1 | mus-81 | F10G8.7.2 | C43E11.2a.1 | ERCC (DNA excision repair protein) homolog. | ERCC4 domain-containing protein. | 0.997 |
ercc-1 | polh-1 | F10G8.7.2 | F53A3.2.1 | ERCC (DNA excision repair protein) homolog. | UmuC domain-containing protein. | 0.677 |
ercc-1 | slx-1 | F10G8.7.2 | F56A3.2.1 | ERCC (DNA excision repair protein) homolog. | Structure-specific endonuclease subunit SLX1 homolog; Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA (Potential). Has a preference for replication forks over 5' flap structures or Holliday junctions and shows much lower activity toward 3' flap structures. Required for proper crossover distribution through inhibition of crossover formation at the c [...] | 0.987 |
ercc-1 | smo-1 | F10G8.7.2 | K12C11.2.1 | ERCC (DNA excision repair protein) homolog. | Small ubiquitin-related modifier; Ubiquitin-like protein which can be covalently attached to target lysines as a monomer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex aos-1-uba-2 and linkage to the E2 enzyme ubc-9, and can be promoted by an E3 ligase such as gei-17. Required for embryonic dev [...] | 0.464 |
ercc-1 | xpf-1 | F10G8.7.2 | C47D12.8.1 | ERCC (DNA excision repair protein) homolog. | ERCC4 domain-containing protein. | 0.999 |
gen-1 | eme-1 | T12A2.8.2 | F56A6.4a.1 | GEN1 Holliday junction resolvase homolog. | Essential Meiotic Endonuclease. | 0.806 |
gen-1 | ercc-1 | T12A2.8.2 | F10G8.7.2 | GEN1 Holliday junction resolvase homolog. | ERCC (DNA excision repair protein) homolog. | 0.927 |
gen-1 | him-18 | T12A2.8.2 | T04A8.15.1 | GEN1 Holliday junction resolvase homolog. | High Incidence of Males (Increased X chromosome loss). | 0.921 |