STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mrp-2Uncharacterized protein. (1525 aa)    
Predicted Functional Partners:
cft-1
Cystic Fibrosis Transmembrane conductance regulator homolog.
  
 
 
0.917
mrp-1
Uncharacterized protein.
  
 
0.905
col-39
Cuticle collagen 39; Nematode cuticles are composed largely of collagen-like proteins. The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment (By similarity).
      
 0.660
nhr-11
Nuclear hormone receptor family member nhr-11; Orphan nuclear receptor.
   
  
 0.626
C14B1.3
Uncharacterized protein.
   
 
 0.601
nas-1
Zinc metalloproteinase nas-1; Metalloprotease.
      
 0.531
irk-1
Inward rectifier potassium channel irk-1; Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Required for modulation of the activity of the hermaphrodite-specific neurons (HSNs) by the G-protein coupled neuropeptide receptor egl-6 which in turn controls egg-laying behavior.
   
 
 0.525
irk-2
Inward Rectifying K (Potassium) channel family.
   
 
 0.515
C23H4.6
AAA_23 domain-containing protein.
   
 
 0.512
mrp-5
Uncharacterized protein.
  
  
0.487
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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