node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
F30F8.9 | bet-2 | F30F8.9a.1 | F57C7.1a.1 | LETM1 domain-containing protein. | BET (Two bromodomains) family protein. | 0.856 |
F30F8.9 | clp-1 | F30F8.9a.1 | C06G4.2a.2 | LETM1 domain-containing protein. | Calpain clp-1; Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates (By similarity). Required for assembly and maintenance of integrin attachment complexes which are essential for maintenance of adult muscle. Proteolytic activity is activated in response to increased intracellular Ca(2+) levels during cell degeneration and promotes necrotic cell death. | 0.690 |
F30F8.9 | coq-2 | F30F8.9a.1 | F57B9.4a.1 | LETM1 domain-containing protein. | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate; Belongs to the UbiA prenyltransferase family. | 0.705 |
F30F8.9 | del-6 | F30F8.9a.1 | T21C9.3b.1 | LETM1 domain-containing protein. | DEgenerin Like; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. | 0.810 |
F30F8.9 | gck-1 | F30F8.9a.1 | T19A5.2b.1 | LETM1 domain-containing protein. | Germinal center kinase 1; Serine/threonine-protein kinase which is required for normal oogenesis and suppression of germline cell apoptosis. Inhibits phosphorylation and thus probably activation of mpk-1 during pachytene stage. Involved in excretory canal elongation during postembryonic development, probably acting downstream of ccm-3 ; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. | 0.696 |
F30F8.9 | gly-5 | F30F8.9a.1 | Y39E4B.12a.1 | LETM1 domain-containing protein. | Polypeptide N-acetylgalactosaminyltransferase 5; Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. | 0.536 |
F30F8.9 | gly-6 | F30F8.9a.1 | H38K22.5a.2 | LETM1 domain-containing protein. | Probable N-acetylgalactosaminyltransferase 6; Probable glycopeptide transferase involved in O-linked oligosaccharide biosynthesis. Glycopeptide transferases catalyze the transfer of an N-acetyl-D-galactosamine residue to an already glycosylated peptide (By similarity). In contrast to other members of the family, it does not act as a peptide transferase that transfers GalNAc onto serine or threonine residue on peptides that have been tested. Some peptide transferase activity is however not excluded, considering that its appropriate peptide substrate may remain unidentified. | 0.618 |
bet-2 | F30F8.9 | F57C7.1a.1 | F30F8.9a.1 | BET (Two bromodomains) family protein. | LETM1 domain-containing protein. | 0.856 |
bet-2 | clp-1 | F57C7.1a.1 | C06G4.2a.2 | BET (Two bromodomains) family protein. | Calpain clp-1; Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates (By similarity). Required for assembly and maintenance of integrin attachment complexes which are essential for maintenance of adult muscle. Proteolytic activity is activated in response to increased intracellular Ca(2+) levels during cell degeneration and promotes necrotic cell death. | 0.586 |
bet-2 | coq-2 | F57C7.1a.1 | F57B9.4a.1 | BET (Two bromodomains) family protein. | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate; Belongs to the UbiA prenyltransferase family. | 0.669 |
bet-2 | csr-1 | F57C7.1a.1 | F20D12.1a.1 | BET (Two bromodomains) family protein. | Piwi domain-containing protein. | 0.629 |
bet-2 | del-6 | F57C7.1a.1 | T21C9.3b.1 | BET (Two bromodomains) family protein. | DEgenerin Like; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. | 0.759 |
bet-2 | gck-1 | F57C7.1a.1 | T19A5.2b.1 | BET (Two bromodomains) family protein. | Germinal center kinase 1; Serine/threonine-protein kinase which is required for normal oogenesis and suppression of germline cell apoptosis. Inhibits phosphorylation and thus probably activation of mpk-1 during pachytene stage. Involved in excretory canal elongation during postembryonic development, probably acting downstream of ccm-3 ; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. | 0.660 |
bet-2 | gly-5 | F57C7.1a.1 | Y39E4B.12a.1 | BET (Two bromodomains) family protein. | Polypeptide N-acetylgalactosaminyltransferase 5; Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. | 0.808 |
bet-2 | gly-6 | F57C7.1a.1 | H38K22.5a.2 | BET (Two bromodomains) family protein. | Probable N-acetylgalactosaminyltransferase 6; Probable glycopeptide transferase involved in O-linked oligosaccharide biosynthesis. Glycopeptide transferases catalyze the transfer of an N-acetyl-D-galactosamine residue to an already glycosylated peptide (By similarity). In contrast to other members of the family, it does not act as a peptide transferase that transfers GalNAc onto serine or threonine residue on peptides that have been tested. Some peptide transferase activity is however not excluded, considering that its appropriate peptide substrate may remain unidentified. | 0.811 |
bet-2 | ncl-1 | F57C7.1a.1 | ZK112.2b.1 | BET (Two bromodomains) family protein. | B-box type zinc finger protein ncl-1; Translational repressor that inhibits protein synthesis. Represses the translation of mRNAs such as fib-1, probably by being recruited by RNA-binding protein nos-2 and the Pumilio proteins puf-5, puf-8 and puf-9 to the consensus core PUF binding motif in the 3'-UTR of fib-1 mRNA. Negatively regulates ribosomal RNA (rRNA) synthesis, ribosomal protein synthesis and nucleolus size. Its role in the negative regulation of nucleolus size is most likely through its negative regulation of the translation of proteins such as the rRNA 2'- O-methyltransferase [...] | 0.589 |
bet-2 | snu-23 | F57C7.1a.1 | ZK686.4.1 | BET (Two bromodomains) family protein. | Putative zinc finger matrin-type protein snu-23. | 0.760 |
clp-1 | F30F8.9 | C06G4.2a.2 | F30F8.9a.1 | Calpain clp-1; Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates (By similarity). Required for assembly and maintenance of integrin attachment complexes which are essential for maintenance of adult muscle. Proteolytic activity is activated in response to increased intracellular Ca(2+) levels during cell degeneration and promotes necrotic cell death. | LETM1 domain-containing protein. | 0.690 |
clp-1 | bet-2 | C06G4.2a.2 | F57C7.1a.1 | Calpain clp-1; Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates (By similarity). Required for assembly and maintenance of integrin attachment complexes which are essential for maintenance of adult muscle. Proteolytic activity is activated in response to increased intracellular Ca(2+) levels during cell degeneration and promotes necrotic cell death. | BET (Two bromodomains) family protein. | 0.586 |
coq-2 | F30F8.9 | F57B9.4a.1 | F30F8.9a.1 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate; Belongs to the UbiA prenyltransferase family. | LETM1 domain-containing protein. | 0.705 |