node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
W03G9.8 | gip-1 | W03G9.8.1 | H04J21.3b.1 | Mitotic spindle organiZing protein (MOZART) homolog. | Gamma-tubulin complex component. | 0.929 |
W03G9.8 | gip-2 | W03G9.8.1 | C45G3.5.1 | Mitotic spindle organiZing protein (MOZART) homolog. | Gamma-tubulin interacting protein 2; Recruited to hemidesomosomes in early embryonic elongation to direct the nucleation and growth of non-centrosomal microtubules. | 0.938 |
W03G9.8 | sas-4 | W03G9.8.1 | F10E9.8.1 | Mitotic spindle organiZing protein (MOZART) homolog. | Spindle assembly abnormal protein 4; Required for centrosome duplication. Plays a central role in determining centrosome size. | 0.475 |
W03G9.8 | spd-5 | W03G9.8.1 | F56A3.4.1 | Mitotic spindle organiZing protein (MOZART) homolog. | Spindle-defective protein 5; Plays a central role in centrosome maturation and mitotic spindle assembly during the first division of the zygote. Required for the centrosomal localization of air-1 and zyg-9. Probably not required in late embryogenesis and during larval development. | 0.695 |
W03G9.8 | tbg-1 | W03G9.8.1 | F58A4.8.1 | Mitotic spindle organiZing protein (MOZART) homolog. | Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome, suggesting that it is involved in the minus-end nucleation of microtubule assembly. | 0.880 |
W03G9.8 | zyg-9 | W03G9.8.1 | F22B5.7.1 | Mitotic spindle organiZing protein (MOZART) homolog. | Zygote defective protein 9; Plays a major role in organizing microtubules and spindle poles during mitosis and meiosis in one-cell stage embryos. Required for default nucleus positioning in oocytes. | 0.669 |
gip-1 | W03G9.8 | H04J21.3b.1 | W03G9.8.1 | Gamma-tubulin complex component. | Mitotic spindle organiZing protein (MOZART) homolog. | 0.929 |
gip-1 | gip-2 | H04J21.3b.1 | C45G3.5.1 | Gamma-tubulin complex component. | Gamma-tubulin interacting protein 2; Recruited to hemidesomosomes in early embryonic elongation to direct the nucleation and growth of non-centrosomal microtubules. | 0.950 |
gip-1 | sas-4 | H04J21.3b.1 | F10E9.8.1 | Gamma-tubulin complex component. | Spindle assembly abnormal protein 4; Required for centrosome duplication. Plays a central role in determining centrosome size. | 0.678 |
gip-1 | spd-5 | H04J21.3b.1 | F56A3.4.1 | Gamma-tubulin complex component. | Spindle-defective protein 5; Plays a central role in centrosome maturation and mitotic spindle assembly during the first division of the zygote. Required for the centrosomal localization of air-1 and zyg-9. Probably not required in late embryogenesis and during larval development. | 0.630 |
gip-1 | tbg-1 | H04J21.3b.1 | F58A4.8.1 | Gamma-tubulin complex component. | Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome, suggesting that it is involved in the minus-end nucleation of microtubule assembly. | 0.999 |
gip-1 | zyg-9 | H04J21.3b.1 | F22B5.7.1 | Gamma-tubulin complex component. | Zygote defective protein 9; Plays a major role in organizing microtubules and spindle poles during mitosis and meiosis in one-cell stage embryos. Required for default nucleus positioning in oocytes. | 0.827 |
gip-2 | W03G9.8 | C45G3.5.1 | W03G9.8.1 | Gamma-tubulin interacting protein 2; Recruited to hemidesomosomes in early embryonic elongation to direct the nucleation and growth of non-centrosomal microtubules. | Mitotic spindle organiZing protein (MOZART) homolog. | 0.938 |
gip-2 | gip-1 | C45G3.5.1 | H04J21.3b.1 | Gamma-tubulin interacting protein 2; Recruited to hemidesomosomes in early embryonic elongation to direct the nucleation and growth of non-centrosomal microtubules. | Gamma-tubulin complex component. | 0.950 |
gip-2 | spd-5 | C45G3.5.1 | F56A3.4.1 | Gamma-tubulin interacting protein 2; Recruited to hemidesomosomes in early embryonic elongation to direct the nucleation and growth of non-centrosomal microtubules. | Spindle-defective protein 5; Plays a central role in centrosome maturation and mitotic spindle assembly during the first division of the zygote. Required for the centrosomal localization of air-1 and zyg-9. Probably not required in late embryogenesis and during larval development. | 0.671 |
gip-2 | tbg-1 | C45G3.5.1 | F58A4.8.1 | Gamma-tubulin interacting protein 2; Recruited to hemidesomosomes in early embryonic elongation to direct the nucleation and growth of non-centrosomal microtubules. | Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome, suggesting that it is involved in the minus-end nucleation of microtubule assembly. | 0.912 |
his-48 | mei-1 | B0035.8.1 | T01G9.5b.1 | Probable histone H2B 4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Meiotic spindle formation protein mei-1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays. Required specifically for meiotic spindle formation in the female germline; the presence of this protein is inimical to the formation of mitotic spindles. In body wall muscles, regulates organization of myosin thick filaments. | 0.509 |
his-48 | pie-1 | B0035.8.1 | Y49E10.14a.1 | Probable histone H2B 4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Pharynx and intestine in excess protein 1; Maternally provided PIE-1 is required for germline cell fate determination. Functions as a repressor of RNA polymerase II-dependent gene expression in the developing germline. Required for expression of nos-2 in P4 germline blastomere cells. Inhibits the histone deacetylase activity of hda-1. Represses transcriptional activation of cdk-9 and cit-1.1, which are members of the P-TEFb complex. | 0.892 |
his-48 | tbg-1 | B0035.8.1 | F58A4.8.1 | Probable histone H2B 4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome, suggesting that it is involved in the minus-end nucleation of microtubule assembly. | 0.811 |
mei-1 | his-48 | T01G9.5b.1 | B0035.8.1 | Meiotic spindle formation protein mei-1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays. Required specifically for meiotic spindle formation in the female germline; the presence of this protein is inimical to the formation of mitotic spindles. In body wall muscles, regulates organization of myosin thick filaments. | Probable histone H2B 4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.509 |