STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
skat-1Probable amino acid transporter skat-1; Plays a role in the accumulation of vital dyes and endogenous fluorescent compounds in lysosome related organelles. Has an effect on lysosome related organelle (LRO) function, in a pathway with serotonin. (460 aa)    
Predicted Functional Partners:
F13H10.3
Sodium-coupled neutral amino acid transporter 9 homolog; Lysosomal amino acid transporter involved in the activation of mTORC1 in response to amino acid levels. Probably acts as an amino acid sensor of the Rag GTPases and Ragulator complexes, 2 complexes involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids.
   
 
 0.921
F59B2.3
N-acetylglucosamine-6-phosphate deacetylase; Belongs to the metallo-dependent hydrolases superfamily. NagA family.
 
    
 0.916
rpn-6.2
Probable 26S proteasome regulatory subunit rpn-6.2; Component of the lid subcomplex of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. In the complex, rpn-6.2 is required for proteasome assembly (By similarity).
      
 0.850
acp-5
ACid Phosphatase family; Belongs to the histidine acid phosphatase family.
      
 0.809
T19D2.2
Putative prenylated protein tyrosine phosphatase.
      
 0.806
Y57A10A.14
Uncharacterized protein.
      
 0.806
kel-1
BTB domain-containing protein.
      
 0.758
taf-6.1
TAF domain-containing protein.
   
  
 0.701
K09C4.5
MFS domain-containing protein.
   
  
 0.700
obr-2
Oxysterol-binding protein; Belongs to the OSBP family.
      
 0.697
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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