node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
R06F6.8 | gdi-1 | R06F6.8b.1 | Y57G11C.10b.1 | Guanine nucleotide exchange factor subunit R06F6.8; Probable component of a guanine nucleotide exchange factor (GEF) that may be required for efficient fusion of endosome-derived vesicles with the Golgi; Belongs to the RIC1 family. | Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. | 0.460 |
R06F6.8 | rab-6.1 | R06F6.8b.1 | F59B2.7.1 | Guanine nucleotide exchange factor subunit R06F6.8; Probable component of a guanine nucleotide exchange factor (GEF) that may be required for efficient fusion of endosome-derived vesicles with the Golgi; Belongs to the RIC1 family. | Ras-related protein Rab-6.1; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family. | 0.844 |
R06F6.8 | rab-6.2 | R06F6.8b.1 | T25G12.4.1 | Guanine nucleotide exchange factor subunit R06F6.8; Probable component of a guanine nucleotide exchange factor (GEF) that may be required for efficient fusion of endosome-derived vesicles with the Golgi; Belongs to the RIC1 family. | Ras-related protein Rab-6.2; Protein transport. Probably involved in vesicular traffic (By similarity). | 0.844 |
bicd-1 | rab-6.1 | C43G2.2a.1 | F59B2.7.1 | Protein bicaudal D homolog; Part of a complex with dlc-1 and egal-1, which is recruited to the nuclear envelope by unc-83, where in turn, it recruits dynein to the nuclear surface and regulates nuclear migration in hypodermal precursor cells (Probable). Required for the formation of dendritic branches of PVD sensory neurons ; Belongs to the BicD family. | Ras-related protein Rab-6.1; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family. | 0.878 |
bicd-1 | rab-6.2 | C43G2.2a.1 | T25G12.4.1 | Protein bicaudal D homolog; Part of a complex with dlc-1 and egal-1, which is recruited to the nuclear envelope by unc-83, where in turn, it recruits dynein to the nuclear surface and regulates nuclear migration in hypodermal precursor cells (Probable). Required for the formation of dendritic branches of PVD sensory neurons ; Belongs to the BicD family. | Ras-related protein Rab-6.2; Protein transport. Probably involved in vesicular traffic (By similarity). | 0.878 |
cogc-6 | rab-6.1 | K07C11.9.1 | F59B2.7.1 | Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function. | Ras-related protein Rab-6.1; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family. | 0.753 |
cogc-6 | rab-6.2 | K07C11.9.1 | T25G12.4.1 | Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function. | Ras-related protein Rab-6.2; Protein transport. Probably involved in vesicular traffic (By similarity). | 0.742 |
cogc-6 | vps-33.1 | K07C11.9.1 | B0303.9.1 | Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function. | Vacuolar protein sorting-associated protein 33A; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways. Believed to act as a component of the putative HOPS endosomal tethering complex which is proposed to be involved in the rab-5-to-rab-7 endosome conversion probably implicating sand-1, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE- mediated membrane fusion. The HOPS complex is proposed to be recruited to rab-7 on the late endosomal membrane and to regulate lat [...] | 0.417 |
cogc-6 | vps-33.2 | K07C11.9.1 | C56C10.1.1 | Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function. | Vacuolar protein sorting-associated protein 33B; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion reactions of late endosomes/lysosomes. Believed to act as a component of the putative CORVET endosomal tethering complex which is proposed to be involved in the rab-5-to-rab-7 endosome conversion probably implicating sand-1, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The CORVET complex is proposed to function as a rab-5 effector to mediate early endoso [...] | 0.422 |
cogc-6 | vps-52 | K07C11.9.1 | F08C6.3.1 | Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function. | Vacuolar protein sorting-associated protein 52 homolog; Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex facilitates tethering as well as SNARE complex assembly at the Golgi. Plays a role in the trafficking of cargo to dense-core vesicles, probably through association with the EARP-interacting protein eipr-1. Important for neuronal function. Belongs to the VPS52 family. | 0.698 |
gdi-1 | R06F6.8 | Y57G11C.10b.1 | R06F6.8b.1 | Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. | Guanine nucleotide exchange factor subunit R06F6.8; Probable component of a guanine nucleotide exchange factor (GEF) that may be required for efficient fusion of endosome-derived vesicles with the Golgi; Belongs to the RIC1 family. | 0.460 |
gdi-1 | rab-6.1 | Y57G11C.10b.1 | F59B2.7.1 | Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. | Ras-related protein Rab-6.1; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family. | 0.952 |
gdi-1 | rab-6.2 | Y57G11C.10b.1 | T25G12.4.1 | Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. | Ras-related protein Rab-6.2; Protein transport. Probably involved in vesicular traffic (By similarity). | 0.953 |
rab-6.1 | R06F6.8 | F59B2.7.1 | R06F6.8b.1 | Ras-related protein Rab-6.1; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family. | Guanine nucleotide exchange factor subunit R06F6.8; Probable component of a guanine nucleotide exchange factor (GEF) that may be required for efficient fusion of endosome-derived vesicles with the Golgi; Belongs to the RIC1 family. | 0.844 |
rab-6.1 | bicd-1 | F59B2.7.1 | C43G2.2a.1 | Ras-related protein Rab-6.1; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family. | Protein bicaudal D homolog; Part of a complex with dlc-1 and egal-1, which is recruited to the nuclear envelope by unc-83, where in turn, it recruits dynein to the nuclear surface and regulates nuclear migration in hypodermal precursor cells (Probable). Required for the formation of dendritic branches of PVD sensory neurons ; Belongs to the BicD family. | 0.878 |
rab-6.1 | cogc-6 | F59B2.7.1 | K07C11.9.1 | Ras-related protein Rab-6.1; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family. | Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function. | 0.753 |
rab-6.1 | gdi-1 | F59B2.7.1 | Y57G11C.10b.1 | Ras-related protein Rab-6.1; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family. | Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. | 0.952 |
rab-6.1 | rab-6.2 | F59B2.7.1 | T25G12.4.1 | Ras-related protein Rab-6.1; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family. | Ras-related protein Rab-6.2; Protein transport. Probably involved in vesicular traffic (By similarity). | 0.881 |
rab-6.1 | tbc-11 | F59B2.7.1 | F35H12.2b.1 | Ras-related protein Rab-6.1; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family. | Rab-GAP TBC domain-containing protein. | 0.852 |
rab-6.1 | vps-33.1 | F59B2.7.1 | B0303.9.1 | Ras-related protein Rab-6.1; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family. | Vacuolar protein sorting-associated protein 33A; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways. Believed to act as a component of the putative HOPS endosomal tethering complex which is proposed to be involved in the rab-5-to-rab-7 endosome conversion probably implicating sand-1, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE- mediated membrane fusion. The HOPS complex is proposed to be recruited to rab-7 on the late endosomal membrane and to regulate lat [...] | 0.768 |