STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F59C12.3Protein F59C12.3 (F59C12.3) mRNA, complete cds (519 aa)    
Predicted Functional Partners:
T25D1.2
Protein T25D1.2 (T25D1.2) mRNA, complete cds
      
 0.892
nfm-1
NeuroFibroMatosis homolog; Protein NFM-1, isoform a
   
 
 0.846
ztf-19
Paralysed Arrest at Two-fold; Protein PAT-9 (pat-9) mRNA, complete cds
   
  
 0.805
Y55F3AM.3
Protein Y55F3AM.3, isoform a
      
 0.762
mab-21
Protein male abnormal 21; Acts in a cell autonomous fashion to specify the properties of the sensory ray and non-autonomously in the choice of hypodermal versus neuroblast cell fate; Belongs to the mab-21 family
      
 0.724
magu-4
MAGUK family; Protein MAGU-4 (magu-4) mRNA, complete cds
   
 
 0.708
mpz-1
Multiple PDZ domain protein; Protein MPZ-1, isoform b (C52A11.5) mRNA, complete cds
   
 
 0.646
magu-2
MAGUK family; Protein MAGU-2 (magu-2) mRNA, complete cds
   
 
 0.634
spdl-1
Spindly-like protein spdl-1; Transient kinetochore component required for chromosome and spindle pole alignment and chromosome segregation during mitosis. Functions downstream of the RZZ complex to mediate kinetochore-microtubule attachments and nuclear envelope breakdown during cell division. Required for kinetochore assembly and localizes the checkpoint proteins mdf-1 and mdf-2, dynein and dynactin to unattached kinetochores. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end [...]
    
   0.633
C15C7.5
Protein C15C7.5 (C15C7.5) mRNA, complete cds
    
   0.633
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Caenorhabditis elegans, Rhabditis elegans, roundworm
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