node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
E01G4.6 | bli-1 | E01G4.6.1 | C09G5.6.1 | Uncharacterized protein. | Cuticle collagen bli-1; Nematode cuticles are composed largely of collagen-like proteins. The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment. This collagen is required for proper strut formation within the unique medial layer of the adult cuticle. | 0.846 |
E01G4.6 | bli-2 | E01G4.6.1 | F59E12.12.1 | Uncharacterized protein. | Col_cuticle_N domain-containing protein. | 0.824 |
E01G4.6 | col-110 | E01G4.6.1 | F19C7.7.1 | Uncharacterized protein. | Col_cuticle_N domain-containing protein. | 0.538 |
E01G4.6 | col-49 | E01G4.6.1 | K09H9.3.1 | Uncharacterized protein. | Col_cuticle_N domain-containing protein. | 0.829 |
bli-1 | E01G4.6 | C09G5.6.1 | E01G4.6.1 | Cuticle collagen bli-1; Nematode cuticles are composed largely of collagen-like proteins. The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment. This collagen is required for proper strut formation within the unique medial layer of the adult cuticle. | Uncharacterized protein. | 0.846 |
bli-1 | bli-2 | C09G5.6.1 | F59E12.12.1 | Cuticle collagen bli-1; Nematode cuticles are composed largely of collagen-like proteins. The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment. This collagen is required for proper strut formation within the unique medial layer of the adult cuticle. | Col_cuticle_N domain-containing protein. | 0.904 |
bli-1 | col-110 | C09G5.6.1 | F19C7.7.1 | Cuticle collagen bli-1; Nematode cuticles are composed largely of collagen-like proteins. The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment. This collagen is required for proper strut formation within the unique medial layer of the adult cuticle. | Col_cuticle_N domain-containing protein. | 0.515 |
bli-1 | col-49 | C09G5.6.1 | K09H9.3.1 | Cuticle collagen bli-1; Nematode cuticles are composed largely of collagen-like proteins. The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment. This collagen is required for proper strut formation within the unique medial layer of the adult cuticle. | Col_cuticle_N domain-containing protein. | 0.590 |
bli-2 | E01G4.6 | F59E12.12.1 | E01G4.6.1 | Col_cuticle_N domain-containing protein. | Uncharacterized protein. | 0.824 |
bli-2 | bli-1 | F59E12.12.1 | C09G5.6.1 | Col_cuticle_N domain-containing protein. | Cuticle collagen bli-1; Nematode cuticles are composed largely of collagen-like proteins. The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment. This collagen is required for proper strut formation within the unique medial layer of the adult cuticle. | 0.904 |
bli-2 | bli-3 | F59E12.12.1 | F56C11.1.1 | Col_cuticle_N domain-containing protein. | Dual oxidase 1; Plays a role in cuticle biogenesis. In complex with doxa-1 and tsp-15, produces reactive oxygen species (ROS), which are probably used by mlt-7 for tyrosine cross-linking, thus stabilizing cuticular extracellular matrix. May regulate the production of ROS by playing a role in modulating proline catabolism. Required in combination with mlt-7 for correct formation of cross-links in cuticle collagens. Association with the GTPase rho-1 promotes ROS production and this interaction may be modulated by memo-1, in order to control the oxidative stress response and longevity. In [...] | 0.763 |
bli-2 | col-110 | F59E12.12.1 | F19C7.7.1 | Col_cuticle_N domain-containing protein. | Col_cuticle_N domain-containing protein. | 0.706 |
bli-2 | col-49 | F59E12.12.1 | K09H9.3.1 | Col_cuticle_N domain-containing protein. | Col_cuticle_N domain-containing protein. | 0.753 |
bli-2 | doxa-1 | F59E12.12.1 | C06E1.3.1 | Col_cuticle_N domain-containing protein. | Dual oxidase maturation factor 1; Plays a role in cuticle biogenesis. In complex with tsp-15 and the dual oxidase bli-3, promotes the generation of reactive oxygen species (ROS) and tyrosine cross-linking of collagen, thus stabilizing cuticular extracellular matrix. | 0.700 |
bli-2 | duox-2 | F59E12.12.1 | F53G12.3.1 | Col_cuticle_N domain-containing protein. | DUal OXidase. | 0.663 |
bli-2 | skpo-2 | F59E12.12.1 | C16C8.2.1 | Col_cuticle_N domain-containing protein. | ShK domain and PerOxidase domain containing protein. | 0.672 |
bli-2 | skpo-3 | F59E12.12.1 | F32A5.2a.1 | Col_cuticle_N domain-containing protein. | ShKT domain-containing protein. | 0.666 |
bli-2 | unc-32 | F59E12.12.1 | ZK637.8a.1 | Col_cuticle_N domain-containing protein. | Probable V-type proton ATPase 116 kDa subunit a; Required for assembly and activity of the vacuolar ATPase. Potential role in differential targeting and regulation of the enzyme for a specific organelle (Probable). Regulates the size of gut granules during embryonic development. | 0.666 |
bli-3 | bli-2 | F56C11.1.1 | F59E12.12.1 | Dual oxidase 1; Plays a role in cuticle biogenesis. In complex with doxa-1 and tsp-15, produces reactive oxygen species (ROS), which are probably used by mlt-7 for tyrosine cross-linking, thus stabilizing cuticular extracellular matrix. May regulate the production of ROS by playing a role in modulating proline catabolism. Required in combination with mlt-7 for correct formation of cross-links in cuticle collagens. Association with the GTPase rho-1 promotes ROS production and this interaction may be modulated by memo-1, in order to control the oxidative stress response and longevity. In [...] | Col_cuticle_N domain-containing protein. | 0.763 |
bli-3 | doxa-1 | F56C11.1.1 | C06E1.3.1 | Dual oxidase 1; Plays a role in cuticle biogenesis. In complex with doxa-1 and tsp-15, produces reactive oxygen species (ROS), which are probably used by mlt-7 for tyrosine cross-linking, thus stabilizing cuticular extracellular matrix. May regulate the production of ROS by playing a role in modulating proline catabolism. Required in combination with mlt-7 for correct formation of cross-links in cuticle collagens. Association with the GTPase rho-1 promotes ROS production and this interaction may be modulated by memo-1, in order to control the oxidative stress response and longevity. In [...] | Dual oxidase maturation factor 1; Plays a role in cuticle biogenesis. In complex with tsp-15 and the dual oxidase bli-3, promotes the generation of reactive oxygen species (ROS) and tyrosine cross-linking of collagen, thus stabilizing cuticular extracellular matrix. | 0.970 |