STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
acox-1.6Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (667 aa)    
Predicted Functional Partners:
maoc-1
MAO-C-like dehydratase domain.
  
 0.994
dhs-28
SCP2 domain-containing protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 0.992
daf-22
Non-specific lipid-transfer protein-like 2; Catalyzes the thiolytic cleavage of 3-ketoacyl-CoA with 8-16 carbon residues in the acyl group using a ping-pong mechanism whereby binding to 3-ketooctanoyl-CoA results in the release of acetyl-CoA and the subsequent addition of CoA produces 3-ketohexanohyl-CoA. Involved in the biosynthesis of the dauer pheromone by providing short chains of fatty acid that are attached to the ascarylose sugars of the pheromone. Belongs to the thiolase-like superfamily. Thiolase family.
   
 0.987
T02G5.7
Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.985
kat-1
Acetyl-CoA acetyltransferase homolog, mitochondrial; Plays a role in ketone body metabolism (By similarity). Has an effect on lysosome related organelles (LRO) function, in a pathway with serotonin. Acts downstream of sir-2.1 to regulate aging and stress resistance. Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.978
B0303.3
Uncharacterized protein B0303.3; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.971
acs-19
Acetyl-coenzyme A synthetase.
  
 
 0.969
acaa-2
ACetyl-CoA Acyltransferase 2 homolog; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.969
C32E8.9
Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 0.967
ech-8
Enoyl-CoA Hydratase.
  
 0.967
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.