STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H27A22.1Peptidase_M28 domain-containing protein. (356 aa)    
Predicted Functional Partners:
zhit-3
HIT-type domain-containing protein.
      
 0.884
C06G3.6
ZZ-type domain-containing protein.
      
 0.808
sqst-3
ZZ-type domain-containing protein.
      
 0.758
sqst-4
ZZ-type domain-containing protein.
      
 0.758
sqst-2
ZZ-type domain-containing protein.
      
 0.758
zipt-7.2
Zinc transporter zipt-7.2; Zinc transporter.
   
  
 0.704
H19N07.3
Uncharacterized protein.
      
 0.698
cup-15
Coelomocyte uptake defective protein 15; Modulates the transport of substances from the endosomal to lysosomal compartments. Plays a role in lysosome formation and function in coelomocytes.
   
  
 0.646
natc-1
N-alpha-AcetylTransferase C complex subunit.
   
  
 0.646
hizr-1
High zinc activated nuclear receptor protein; Nuclear receptor transcription factor that binds to DNA enhancer elements to promote the transcription of genes required to maintain micronutrient homeostasis. Direct binding to its ligand zinc allows for nuclear accumulation and activation, which thereby induces the transcription of genes required to promote the storage and detoxification of excess dietary zinc. This in turn, allows for internal zinc levels to be detected and regulated.
      
 0.636
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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