node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
E01A2.1 | T09B4.8 | E01A2.1b.1 | T09B4.8.1 | Aldo_ket_red domain-containing protein. | Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.904 |
E01A2.1 | Y44A6D.5 | E01A2.1b.1 | Y44A6D.5.1 | Aldo_ket_red domain-containing protein. | Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.904 |
E01A2.1 | bcat-1 | E01A2.1b.1 | K02A4.1.1 | Aldo_ket_red domain-containing protein. | Branched-chain-amino-acid aminotransferase, cytosolic; Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.904 |
E01A2.1 | cth-1 | E01A2.1b.1 | F22B8.6a.1 | Aldo_ket_red domain-containing protein. | CystaTHionine gamma lyase. | 0.825 |
E01A2.1 | cth-2 | E01A2.1b.1 | ZK1127.10.2 | Aldo_ket_red domain-containing protein. | Putative cystathionine gamma-lyase 2; Belongs to the trans-sulfuration enzymes family. | 0.825 |
F25B5.6 | Y44A6D.5 | F25B5.6b.1 | Y44A6D.5.1 | Putative folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.895 |
F25B5.6 | bcat-1 | F25B5.6b.1 | K02A4.1.1 | Putative folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Branched-chain-amino-acid aminotransferase, cytosolic; Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.928 |
T09B4.8 | E01A2.1 | T09B4.8.1 | E01A2.1b.1 | Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Aldo_ket_red domain-containing protein. | 0.904 |
T09B4.8 | Y44A6D.5 | T09B4.8.1 | Y44A6D.5.1 | Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.942 |
T09B4.8 | bcat-1 | T09B4.8.1 | K02A4.1.1 | Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Branched-chain-amino-acid aminotransferase, cytosolic; Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.943 |
T09B4.8 | bckd-1A | T09B4.8.1 | Y39E4A.3b.1 | Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). Required for the production of the monomethyl branched-chain fatty acids (mmBCFAs) isopentadecanoate (C15iso) and isoheptadecanoate (C17iso). | 0.826 |
T09B4.8 | bckd-1B | T09B4.8.1 | F27D4.5.1 | Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Transket_pyr domain-containing protein. | 0.860 |
T09B4.8 | cth-1 | T09B4.8.1 | F22B8.6a.1 | Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | CystaTHionine gamma lyase. | 0.923 |
T09B4.8 | cth-2 | T09B4.8.1 | ZK1127.10.2 | Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Putative cystathionine gamma-lyase 2; Belongs to the trans-sulfuration enzymes family. | 0.924 |
Y43F4A.4 | Y44A6D.5 | Y43F4A.4.1 | Y44A6D.5.1 | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.785 |
Y43F4A.4 | Y71G12B.10 | Y43F4A.4.1 | Y71G12B.10.1 | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | Pyruvate carboxyltransferase domain-containing protein. | 0.563 |
Y43F4A.4 | bcat-1 | Y43F4A.4.1 | K02A4.1.1 | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | Branched-chain-amino-acid aminotransferase, cytosolic; Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.905 |
Y43F4A.4 | bckd-1A | Y43F4A.4.1 | Y39E4A.3b.1 | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). Required for the production of the monomethyl branched-chain fatty acids (mmBCFAs) isopentadecanoate (C15iso) and isoheptadecanoate (C17iso). | 0.545 |
Y43F4A.4 | bckd-1B | Y43F4A.4.1 | F27D4.5.1 | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | Transket_pyr domain-containing protein. | 0.999 |
Y44A6D.5 | E01A2.1 | Y44A6D.5.1 | E01A2.1b.1 | Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | Aldo_ket_red domain-containing protein. | 0.904 |