node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
aqp-8 | ceh-6 | K02G10.7b.1 | K02B12.1.1 | AQuaPorin or aquaglyceroporin related; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Homeobox protein ceh-6; Vital for embryonic development and essential for the proper function of the excretory cell. Required for the transdifferentiation of the Y rectal epithelial cell to the PDA motor neuron during larval development. | 0.694 |
aqp-8 | twk-23 | K02G10.7b.1 | F19D8.1b.1 | AQuaPorin or aquaglyceroporin related; Belongs to the MIP/aquaporin (TC 1.A.8) family. | TWiK family of potassium channels; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. | 0.694 |
ceh-32 | ceh-6 | W05E10.3.1 | K02B12.1.1 | Homeobox protein ceh-32; Plays a role in head morphogenesis, expression is regulated by vab-3. | Homeobox protein ceh-6; Vital for embryonic development and essential for the proper function of the excretory cell. Required for the transdifferentiation of the Y rectal epithelial cell to the PDA motor neuron during larval development. | 0.669 |
ceh-32 | ceh-8 | W05E10.3.1 | ZK265.4a.1 | Homeobox protein ceh-32; Plays a role in head morphogenesis, expression is regulated by vab-3. | Homeobox protein ceh-8. | 0.854 |
ceh-32 | egl-5 | W05E10.3.1 | C08C3.1b.1 | Homeobox protein ceh-32; Plays a role in head morphogenesis, expression is regulated by vab-3. | Homeobox protein egl-5; Essential for the determination of specific neurons. | 0.400 |
ceh-32 | ets-5 | W05E10.3.1 | C42D8.4b.1 | Homeobox protein ceh-32; Plays a role in head morphogenesis, expression is regulated by vab-3. | ETS domain-containing transcription factor ets-5; Transcription factor that plays a role in the differentiation and function of the CO(2)- and O(2)-sensing BAG neurons. The BAG neurons are required for the behavioral avoidance of environmental CO(2) and the sensing of decreased O(2) levels. Promotes the expression of genes that play a role in CO(2)- and O(2)-sensing and in egg-laying in the BAG neurons. Positively regulates the transcription of the receptor-type guanylate cyclase gcy-9, which is a critical component of the CO(2) transduction pathway, in the BAG neurons. May mediate tra [...] | 0.631 |
ceh-32 | nhr-104 | W05E10.3.1 | R11E3.5a.1 | Homeobox protein ceh-32; Plays a role in head morphogenesis, expression is regulated by vab-3. | NR LBD domain-containing protein. | 0.478 |
ceh-32 | sox-2 | W05E10.3.1 | K08A8.2a.2 | Homeobox protein ceh-32; Plays a role in head morphogenesis, expression is regulated by vab-3. | Transcription factor sox-2; Probable transcription factor that regulates the lineage progression of embryonic blast cells and controls the postmitotic specification and differentiation of neurons. Cooperates with additional factors to direct the differentiation of the olfactory neurons, functioning with the transcription factor ceh-36 to specify AWC neurons and with the LIM homeodomain factor lim-4 to suppress AWC terminal differentiation and promote AWB neuron differentiation. Plays a role in the terminal differentiation of glutamatergic and cholinergic neurons. Required for natural r [...] | 0.485 |
ceh-6 | aqp-8 | K02B12.1.1 | K02G10.7b.1 | Homeobox protein ceh-6; Vital for embryonic development and essential for the proper function of the excretory cell. Required for the transdifferentiation of the Y rectal epithelial cell to the PDA motor neuron during larval development. | AQuaPorin or aquaglyceroporin related; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.694 |
ceh-6 | ceh-32 | K02B12.1.1 | W05E10.3.1 | Homeobox protein ceh-6; Vital for embryonic development and essential for the proper function of the excretory cell. Required for the transdifferentiation of the Y rectal epithelial cell to the PDA motor neuron during larval development. | Homeobox protein ceh-32; Plays a role in head morphogenesis, expression is regulated by vab-3. | 0.669 |
ceh-6 | ceh-8 | K02B12.1.1 | ZK265.4a.1 | Homeobox protein ceh-6; Vital for embryonic development and essential for the proper function of the excretory cell. Required for the transdifferentiation of the Y rectal epithelial cell to the PDA motor neuron during larval development. | Homeobox protein ceh-8. | 0.671 |
ceh-6 | egl-27 | K02B12.1.1 | C04A2.3a.1 | Homeobox protein ceh-6; Vital for embryonic development and essential for the proper function of the excretory cell. Required for the transdifferentiation of the Y rectal epithelial cell to the PDA motor neuron during larval development. | Egg-laying defective protein 27; Transcription factor which promotes stress survival and delays aging. Required for cell cycle progression and development of the mesodermal and endodermal embryonic lineages. Required for normal T-cell polarity, for correct migration of QL neuroblast descendants and other cells, for embryonic patterning and for the embryonic expression of hlh-8. Also required for the transdifferentiation of the Y rectal epithelial cell to the PDA motor neuron during larval development. | 0.960 |
ceh-6 | egl-5 | K02B12.1.1 | C08C3.1b.1 | Homeobox protein ceh-6; Vital for embryonic development and essential for the proper function of the excretory cell. Required for the transdifferentiation of the Y rectal epithelial cell to the PDA motor neuron during larval development. | Homeobox protein egl-5; Essential for the determination of specific neurons. | 0.608 |
ceh-6 | ets-5 | K02B12.1.1 | C42D8.4b.1 | Homeobox protein ceh-6; Vital for embryonic development and essential for the proper function of the excretory cell. Required for the transdifferentiation of the Y rectal epithelial cell to the PDA motor neuron during larval development. | ETS domain-containing transcription factor ets-5; Transcription factor that plays a role in the differentiation and function of the CO(2)- and O(2)-sensing BAG neurons. The BAG neurons are required for the behavioral avoidance of environmental CO(2) and the sensing of decreased O(2) levels. Promotes the expression of genes that play a role in CO(2)- and O(2)-sensing and in egg-laying in the BAG neurons. Positively regulates the transcription of the receptor-type guanylate cyclase gcy-9, which is a critical component of the CO(2) transduction pathway, in the BAG neurons. May mediate tra [...] | 0.618 |
ceh-6 | nhr-104 | K02B12.1.1 | R11E3.5a.1 | Homeobox protein ceh-6; Vital for embryonic development and essential for the proper function of the excretory cell. Required for the transdifferentiation of the Y rectal epithelial cell to the PDA motor neuron during larval development. | NR LBD domain-containing protein. | 0.668 |
ceh-6 | sem-4 | K02B12.1.1 | F15C11.1.1 | Homeobox protein ceh-6; Vital for embryonic development and essential for the proper function of the excretory cell. Required for the transdifferentiation of the Y rectal epithelial cell to the PDA motor neuron during larval development. | SEM-4 long form. | 0.971 |
ceh-6 | sox-2 | K02B12.1.1 | K08A8.2a.2 | Homeobox protein ceh-6; Vital for embryonic development and essential for the proper function of the excretory cell. Required for the transdifferentiation of the Y rectal epithelial cell to the PDA motor neuron during larval development. | Transcription factor sox-2; Probable transcription factor that regulates the lineage progression of embryonic blast cells and controls the postmitotic specification and differentiation of neurons. Cooperates with additional factors to direct the differentiation of the olfactory neurons, functioning with the transcription factor ceh-36 to specify AWC neurons and with the LIM homeodomain factor lim-4 to suppress AWC terminal differentiation and promote AWB neuron differentiation. Plays a role in the terminal differentiation of glutamatergic and cholinergic neurons. Required for natural r [...] | 0.913 |
ceh-6 | twk-23 | K02B12.1.1 | F19D8.1b.1 | Homeobox protein ceh-6; Vital for embryonic development and essential for the proper function of the excretory cell. Required for the transdifferentiation of the Y rectal epithelial cell to the PDA motor neuron during larval development. | TWiK family of potassium channels; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. | 0.614 |
ceh-8 | ceh-32 | ZK265.4a.1 | W05E10.3.1 | Homeobox protein ceh-8. | Homeobox protein ceh-32; Plays a role in head morphogenesis, expression is regulated by vab-3. | 0.854 |
ceh-8 | ceh-6 | ZK265.4a.1 | K02B12.1.1 | Homeobox protein ceh-8. | Homeobox protein ceh-6; Vital for embryonic development and essential for the proper function of the excretory cell. Required for the transdifferentiation of the Y rectal epithelial cell to the PDA motor neuron during larval development. | 0.671 |