STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gln-2Probable glutamine synthetase. (367 aa)    
Predicted Functional Partners:
F32A11.3
Uncharacterized protein.
   
    0.999
Y38H8A.3
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
    0.999
K06A5.2
Uncharacterized protein.
   
    0.976
W07E11.1
Glutamine amidotransferase type-2 domain-containing protein.
  
 
 0.976
pyr-1
Glutamine-dependent carbamoyl-phosphate synthase; This protein is a 'fusion' protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase) (By similarity). Involved in the elongation of the pharyngeal isthmus during development, probably by providing precursors of UDP- sugars required for heparan sulfate proteoglycan biosynthesis. Regulates the organization of the actin and intermediate filaments cytoskeleton in the pharyngeal muscles ; In the central section; belongs to the metallo-dependent hydrolases superfamily. DHOase family. CAD subfamily.
  
 
 0.971
gdh-1
Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.970
ppat-1
Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
    
 0.955
glna-1
ANK_REP_REGION domain-containing protein.
  
 
 0.950
gfat-2
Glutamine-Fructose 6-phosphate AminoTransferase homolog.
  
 
 0.950
glna-3
Putative glutaminase 3.
  
 
 0.950
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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