STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ptp-4Tyrosine-protein phosphatase 4. (1159 aa)    
Predicted Functional Partners:
igdb-1
Ig-like and fibronectin type-III domain-containing protein 1.
   
 
 0.877
igeg-1
IG (Immunoglobulin), EGF and transmmembrane domain.
   
 
 0.859
zig-11
Ig-like domain-containing protein.
      
 0.850
igcm-3
ImmunoGlobulin-like Cell adhesion Molecule family.
   
  
 0.817
ptps-1
Putative 6-pyruvoyl tetrahydrobiopterin synthase; Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6-pyruvoyl tetrahydropterin (By similarity); Belongs to the PTPS family.
    
 
 0.810
nlp-11
Neuropeptide-like peptide 11.
      
 0.760
trf-1
TNF Receptor Associated Factor (TRAF) homolog.
   
  
 0.739
T14E8.4
Uncharacterized protein.
   
 
 0.733
spe-45
Ig-like domain-containing protein.
      
 0.698
igcm-2
ImmunoGlobulin-like Cell adhesion Molecule family.
   
   0.669
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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