STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
vit-1Vitellogenin-1; Precursor of the egg-yolk proteins that are sources of nutrients during embryonic development. (1616 aa)    
Predicted Functional Partners:
vit-5
Vitellogenin-5; Precursor of the egg-yolk proteins that are sources of nutrients during embryonic development.
   
 
0.836
vit-6
Vitellogenin-6; Precursor of the egg-yolk proteins that are sources of nutrients during embryonic development (Probable). May play a role in cholesterol uptake. May be involved in thermotolerance.
   
 
0.832
dsc-4
Microsomal triglyceride transfer protein.
   
 
 0.766
Y45F10C.4
UPF0375 protein Y45F10C.4.
   
  
 0.757
rme-2
Receptor Mediated Endocytosis.
   
 
 0.753
vit-4
Vitellogenin-4; Precursor of the egg-yolk proteins that are sources of nutrients during embryonic development.
   
 
0.729
vit-2
Vitellogenin-2; Precursor of the egg-yolk proteins that are sources of nutrients during embryonic development.
   
 
0.723
vrp-1
Vitellogenin Regulating Protein.
   
  
 0.721
Y45F10C.2
UPF0375 protein Y45F10C.2; Negatively regulates the egg-laying rate by promoting retention of fertilized eggs.
   
  
 0.619
clec-72
C-type lectin domain-containing protein.
      
 0.613
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.