STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cid-14Fe-4S ferredoxin-type domain-containing protein. (1425 aa)    
Predicted Functional Partners:
K10D2.5
Uncharacterized protein K10D2.5.
      
 0.698
gpb-1
Guanine nucleotide-binding protein subunit beta-1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. In the early embryo, controls the magnitude of the forces acting on centrosomes but is not required for generating asymmetric forces.
   
  
 0.688
C27D9.1
Uncharacterized protein.
   
 
 0.674
lin-28
Protein lin-28; Heterochronic protein which controls the choice of stage specific cell fates. Regulates the timing of the second larval stage events (L2 events) in the hypodermis. May negatively regulate the larval to adult transition via the suppression of the microRNA (miRNA) let-7 during L3. Plays a role in the control of seam cell number and vulval development. Belongs to the lin-28 family.
   
 
 0.642
gpr-2
G-protein regulator 2; In the 1-cell embryo, probably together with gpr-1, controls nuclear rotation and spindle elongation during mitosis. Complex of gpr-1 and gpr-2, in association with lin- 5, activates G-protein signaling to affect mitotic spindle force. Polarity determinants (par genes) may regulate lin- 5/gpr-1/gpr-2/goa-1 locally to create the asymmetric forces that drive spindle movement.
   
  
 0.568
gpr-1
G-protein regulator 1; In the 1-cell embryo, probably together with gpr-2, controls nuclear rotation and spindle elongation during mitosis. Complex of gpr-1 and gpr-2, in association with lin- 5, activates G-protein signaling to affect mitotic spindle force. Polarity determinants (par genes) may regulate lin- 5/gpr-1/gpr-2/goa-1 locally to create the asymmetric forces that drive spindle movement.
   
  
 0.568
ego-1
RNA-directed RNA polymerase related EGO-1.
   
 
 0.552
pap-1
Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's.
   
  
 0.522
pup-3
PAP-associated domain-containing protein.
  
  
0.495
T15H9.6
Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's.
   
  
 0.455
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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