Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Y17G7B.22 | glr-3 | Y17G7B.22.1 | K10D3.1.1 | Uncharacterized protein. | GLutamate Receptor family (AMPA). | 0.700 |
| Y17G7B.22 | twk-3 | Y17G7B.22.1 | M110.2.1 | Uncharacterized protein. | TWiK family of potassium channels; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. | 0.698 |
| cal-2 | dlg-1 | C18E9.1.1 | C25F6.2a.1 | CALmodulin related genes. | Disks large homolog 1; Essential multidomain scaffolding protein required for normal development (Probable). Recruits channels, receptors and signaling molecules to discrete plasma membrane domains in polarized cells (By similarity). Required for proper embryonic elongation. Acts upstream of ajm-1 and becomes localized to apical junctions independently of ajm-1. With let-413, cooperatively regulates ajm-1 localization to apical junctions. Belongs to the MAGUK family. | 0.828 |
| cal-2 | glr-3 | C18E9.1.1 | K10D3.1.1 | CALmodulin related genes. | GLutamate Receptor family (AMPA). | 0.523 |
| cal-2 | glr-6 | C18E9.1.1 | F41B4.4a.1 | CALmodulin related genes. | PBPe domain-containing protein. | 0.518 |
| cal-2 | trpa-1 | C18E9.1.1 | C29E6.2a.1 | CALmodulin related genes. | Transient receptor potential cation channel subfamily A member 1 homolog; Receptor-activated non-selective cation channel involved in the nose-touch response and foraging behavior. Contributes to the neural responses of sensory neurons to touch, particularly after repeated mechanical stimulation. Has no apparent role in thermosensory or chemosensory behaviors. | 0.440 |
| dlg-1 | cal-2 | C25F6.2a.1 | C18E9.1.1 | Disks large homolog 1; Essential multidomain scaffolding protein required for normal development (Probable). Recruits channels, receptors and signaling molecules to discrete plasma membrane domains in polarized cells (By similarity). Required for proper embryonic elongation. Acts upstream of ajm-1 and becomes localized to apical junctions independently of ajm-1. With let-413, cooperatively regulates ajm-1 localization to apical junctions. Belongs to the MAGUK family. | CALmodulin related genes. | 0.828 |
| dlg-1 | glr-3 | C25F6.2a.1 | K10D3.1.1 | Disks large homolog 1; Essential multidomain scaffolding protein required for normal development (Probable). Recruits channels, receptors and signaling molecules to discrete plasma membrane domains in polarized cells (By similarity). Required for proper embryonic elongation. Acts upstream of ajm-1 and becomes localized to apical junctions independently of ajm-1. With let-413, cooperatively regulates ajm-1 localization to apical junctions. Belongs to the MAGUK family. | GLutamate Receptor family (AMPA). | 0.624 |
| dlg-1 | glr-6 | C25F6.2a.1 | F41B4.4a.1 | Disks large homolog 1; Essential multidomain scaffolding protein required for normal development (Probable). Recruits channels, receptors and signaling molecules to discrete plasma membrane domains in polarized cells (By similarity). Required for proper embryonic elongation. Acts upstream of ajm-1 and becomes localized to apical junctions independently of ajm-1. With let-413, cooperatively regulates ajm-1 localization to apical junctions. Belongs to the MAGUK family. | PBPe domain-containing protein. | 0.626 |
| eat-4 | glr-3 | ZK512.6a.1 | K10D3.1.1 | Probable vesicular glutamate transporter eat-4; Required for glutamatergic synaptic transmission. In AWB and AWC sensory neurons, required for the detection of preferred food sources, probably via glutamatergic neurotransmission from sensory neurons. Negatively regulates the turning step of male mating behavior. | GLutamate Receptor family (AMPA). | 0.635 |
| eat-4 | glr-6 | ZK512.6a.1 | F41B4.4a.1 | Probable vesicular glutamate transporter eat-4; Required for glutamatergic synaptic transmission. In AWB and AWC sensory neurons, required for the detection of preferred food sources, probably via glutamatergic neurotransmission from sensory neurons. Negatively regulates the turning step of male mating behavior. | PBPe domain-containing protein. | 0.621 |
| eat-4 | ttx-3 | ZK512.6a.1 | C40H5.5a.1 | Probable vesicular glutamate transporter eat-4; Required for glutamatergic synaptic transmission. In AWB and AWC sensory neurons, required for the detection of preferred food sources, probably via glutamatergic neurotransmission from sensory neurons. Negatively regulates the turning step of male mating behavior. | LIM/homeobox protein ttx-3; Required for specification of the AIA and AIY interneurons and the NSM neurons. Positively regulates the expression of a number of genes including ceh-23, kal-1, hen-1, ser-2, unc-17 and sra-11 in AIY interneurons and cat-4, flp-4, bas-1, ptps-1 and mgl-1 in NSM neurons. Also acts in an autoregulatory feedback loop to maintain its own expression. Plays a role in the thermotactic response, olfactory imprinting, regulation of longevity, control of dauer formation and axon outgrowth and pathfinding. Not required for normal chemosensory behavior. | 0.683 |
| gcy-18 | glr-3 | ZK896.8.1 | K10D3.1.1 | Receptor-type guanylate cyclase gcy-18; Guanylate cyclase involved in the production of the second messenger cGMP (By similarity). Regulates thermotaxis responses in AFD sensory neurons. May regulate AFD neuronal activity such as calcium responses to temperature gradients. | GLutamate Receptor family (AMPA). | 0.542 |
| gcy-18 | trpa-1 | ZK896.8.1 | C29E6.2a.1 | Receptor-type guanylate cyclase gcy-18; Guanylate cyclase involved in the production of the second messenger cGMP (By similarity). Regulates thermotaxis responses in AFD sensory neurons. May regulate AFD neuronal activity such as calcium responses to temperature gradients. | Transient receptor potential cation channel subfamily A member 1 homolog; Receptor-activated non-selective cation channel involved in the nose-touch response and foraging behavior. Contributes to the neural responses of sensory neurons to touch, particularly after repeated mechanical stimulation. Has no apparent role in thermosensory or chemosensory behaviors. | 0.410 |
| gcy-8 | glr-3 | C49H3.1.1 | K10D3.1.1 | Receptor-type guanylate cyclase gcy-8; Guanylate cyclase involved in the production of the second messenger cGMP. Regulates thermotaxis responses in AFD sensory neurons. May regulate AFD neuronal activity such as calcium responses to temperature gradients. Maintains the microvilli receptive ending morphology of the AFD thermosensory neurons by regulating cGMP levels downstream of kcc-3. cGMP levels antagonize the actin cytoskeleton regulator wsp-1. | GLutamate Receptor family (AMPA). | 0.702 |
| gcy-8 | ttx-3 | C49H3.1.1 | C40H5.5a.1 | Receptor-type guanylate cyclase gcy-8; Guanylate cyclase involved in the production of the second messenger cGMP. Regulates thermotaxis responses in AFD sensory neurons. May regulate AFD neuronal activity such as calcium responses to temperature gradients. Maintains the microvilli receptive ending morphology of the AFD thermosensory neurons by regulating cGMP levels downstream of kcc-3. cGMP levels antagonize the actin cytoskeleton regulator wsp-1. | LIM/homeobox protein ttx-3; Required for specification of the AIA and AIY interneurons and the NSM neurons. Positively regulates the expression of a number of genes including ceh-23, kal-1, hen-1, ser-2, unc-17 and sra-11 in AIY interneurons and cat-4, flp-4, bas-1, ptps-1 and mgl-1 in NSM neurons. Also acts in an autoregulatory feedback loop to maintain its own expression. Plays a role in the thermotactic response, olfactory imprinting, regulation of longevity, control of dauer formation and axon outgrowth and pathfinding. Not required for normal chemosensory behavior. | 0.696 |
| glr-3 | Y17G7B.22 | K10D3.1.1 | Y17G7B.22.1 | GLutamate Receptor family (AMPA). | Uncharacterized protein. | 0.700 |
| glr-3 | cal-2 | K10D3.1.1 | C18E9.1.1 | GLutamate Receptor family (AMPA). | CALmodulin related genes. | 0.523 |
| glr-3 | dlg-1 | K10D3.1.1 | C25F6.2a.1 | GLutamate Receptor family (AMPA). | Disks large homolog 1; Essential multidomain scaffolding protein required for normal development (Probable). Recruits channels, receptors and signaling molecules to discrete plasma membrane domains in polarized cells (By similarity). Required for proper embryonic elongation. Acts upstream of ajm-1 and becomes localized to apical junctions independently of ajm-1. With let-413, cooperatively regulates ajm-1 localization to apical junctions. Belongs to the MAGUK family. | 0.624 |
| glr-3 | eat-4 | K10D3.1.1 | ZK512.6a.1 | GLutamate Receptor family (AMPA). | Probable vesicular glutamate transporter eat-4; Required for glutamatergic synaptic transmission. In AWB and AWC sensory neurons, required for the detection of preferred food sources, probably via glutamatergic neurotransmission from sensory neurons. Negatively regulates the turning step of male mating behavior. | 0.635 |
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