node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
apa-2 | apb-1 | T20B5.1.1 | Y71H2B.10a.1 | AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. | AP complex subunit beta. | 0.998 |
apa-2 | apg-1 | T20B5.1.1 | Y105E8A.9.1 | AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. | AP-1 complex subunit gamma. | 0.680 |
apa-2 | apm-1 | T20B5.1.1 | F55A12.7.1 | AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. | MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. | 0.785 |
apa-2 | aps-1 | T20B5.1.1 | F29G9.3.1 | AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. | 0.790 |
apa-2 | unc-101 | T20B5.1.1 | K11D2.3a.2 | AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. | AP-1 complex subunit mu-1-I; Component of the adaptor complexes which link clathrin to receptors in coated vesicles (Probable). Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration (Probable). Required for many aspects of development and behavior, including negative regulation of vulval differentiation. Required for the dendritic localization of potassium channel kvs-4 in the cholinergic motor neuron DA9. | 0.866 |
apa-2 | unc-11 | T20B5.1.1 | C32E8.10c.1 | AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. | Phosphatidylinositol-binding clathrin assembly protein unc-11; Assembly protein recruiting clathrin and adaptor protein complex 2 (AP2) to cell membranes at sites of coated-pit formation and clathrin-vesicle assembly. May be required to determine the amount of membrane to be recycled, possibly by regulating the size of the clathrin cage. Involved in AP2-dependent clathrin-mediated endocytosis at the neuromuscular junction. Required for the efficient targeting of the synaptic vesicle protein synaptobrevin. Belongs to the PICALM/SNAP91 family. | 0.914 |
apb-1 | apa-2 | Y71H2B.10a.1 | T20B5.1.1 | AP complex subunit beta. | AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. | 0.998 |
apb-1 | apg-1 | Y71H2B.10a.1 | Y105E8A.9.1 | AP complex subunit beta. | AP-1 complex subunit gamma. | 0.999 |
apb-1 | apm-1 | Y71H2B.10a.1 | F55A12.7.1 | AP complex subunit beta. | MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. | 0.949 |
apb-1 | aps-1 | Y71H2B.10a.1 | F29G9.3.1 | AP complex subunit beta. | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. | 0.987 |
apb-1 | arf-1.1 | Y71H2B.10a.1 | F45E4.1.1 | AP complex subunit beta. | ADP-ribosylation factor 1-like 1; GTP-binding protein that may be involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus; Belongs to the small GTPase superfamily. Arf family. | 0.804 |
apb-1 | unc-101 | Y71H2B.10a.1 | K11D2.3a.2 | AP complex subunit beta. | AP-1 complex subunit mu-1-I; Component of the adaptor complexes which link clathrin to receptors in coated vesicles (Probable). Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration (Probable). Required for many aspects of development and behavior, including negative regulation of vulval differentiation. Required for the dendritic localization of potassium channel kvs-4 in the cholinergic motor neuron DA9. | 0.978 |
apb-1 | unc-11 | Y71H2B.10a.1 | C32E8.10c.1 | AP complex subunit beta. | Phosphatidylinositol-binding clathrin assembly protein unc-11; Assembly protein recruiting clathrin and adaptor protein complex 2 (AP2) to cell membranes at sites of coated-pit formation and clathrin-vesicle assembly. May be required to determine the amount of membrane to be recycled, possibly by regulating the size of the clathrin cage. Involved in AP2-dependent clathrin-mediated endocytosis at the neuromuscular junction. Required for the efficient targeting of the synaptic vesicle protein synaptobrevin. Belongs to the PICALM/SNAP91 family. | 0.715 |
apg-1 | apa-2 | Y105E8A.9.1 | T20B5.1.1 | AP-1 complex subunit gamma. | AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. | 0.680 |
apg-1 | apb-1 | Y105E8A.9.1 | Y71H2B.10a.1 | AP-1 complex subunit gamma. | AP complex subunit beta. | 0.999 |
apg-1 | apm-1 | Y105E8A.9.1 | F55A12.7.1 | AP-1 complex subunit gamma. | MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. | 0.998 |
apg-1 | aps-1 | Y105E8A.9.1 | F29G9.3.1 | AP-1 complex subunit gamma. | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. | 0.995 |
apg-1 | arf-1.1 | Y105E8A.9.1 | F45E4.1.1 | AP-1 complex subunit gamma. | ADP-ribosylation factor 1-like 1; GTP-binding protein that may be involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus; Belongs to the small GTPase superfamily. Arf family. | 0.925 |
apg-1 | ltah-1.1 | Y105E8A.9.1 | C42C1.11a.1 | AP-1 complex subunit gamma. | Aminopeptidase ltah-1.1; Aminopeptidase which preferentially removes N-terminal Arg and Lys residues from peptides and proteins. | 0.703 |
apg-1 | unc-101 | Y105E8A.9.1 | K11D2.3a.2 | AP-1 complex subunit gamma. | AP-1 complex subunit mu-1-I; Component of the adaptor complexes which link clathrin to receptors in coated vesicles (Probable). Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration (Probable). Required for many aspects of development and behavior, including negative regulation of vulval differentiation. Required for the dendritic localization of potassium channel kvs-4 in the cholinergic motor neuron DA9. | 0.995 |