STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nas-11Zinc metalloproteinase nas-11; Metalloprotease. (579 aa)    
Predicted Functional Partners:
Y16B4A.2
Carboxypeptidase; Belongs to the peptidase S10 family.
   
  
 0.720
C08H9.1
Serine carboxypeptidase ctsa-3.2; Belongs to the peptidase S10 family.
   
  
 0.704
app-1
Xaa-Pro aminopeptidase app-1; Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Arg-Pro-Pro. Has activity towards the flp-9 neuropeptide KPSFVRF- amide.
   
  
 0.696
lap-1
Leucine aminopeptidase 1; Probably acts as a digestive enzyme.
      
 0.541
asp-5
Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family.
   
  
 0.532
asp-2
Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family.
   
  
 0.464
lec-7
Probable galaptin lec-7.
   
  
 0.430
asp-13
Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family.
   
  
 0.416
asp-8
Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family.
   
  
 0.416
zmp-4
ZnMc domain-containing protein.
   
   0.414
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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