node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
alg-1 | alg-2 | F48F7.1b.1 | T07D3.7a.1 | Protein argonaute; Belongs to the argonaute family. | Protein argonaute; Belongs to the argonaute family. | 0.941 |
alg-1 | dcr-1 | F48F7.1b.1 | K12H4.8.2 | Protein argonaute; Belongs to the argonaute family. | Death-promoting deoxyribonuclease; Involved in cleaving double-stranded RNA in the RNA interference (RNAi) pathway. It produces 21 to 23 bp dsRNAs (siRNAs) which target the selective destruction of homologous RNAs. Seems to process the precursor of the small temporal RNA let-7 which is involved in developmental timing. Belongs to the helicase family. Dicer subfamily. | 0.991 |
alg-1 | drh-3 | F48F7.1b.1 | D2005.5.1 | Protein argonaute; Belongs to the argonaute family. | Dicer Related Helicase. | 0.423 |
alg-1 | ergo-1 | F48F7.1b.1 | R09A1.1a.1 | Protein argonaute; Belongs to the argonaute family. | Piwi-like protein ergo-1; Argonaute protein required for gene silencing in the endogenous RNA interference (RNAi) pathway. Involved in the 26G RNAi pathway and associates with both unmethylated and methylated 26G small interfering RNAs (26G- siRNAs), which are a class of 26 nucleotide siRNAs that possess a guanine residue at the 5'-end. Associated 26G-siRNAs are methylated by the methyltransferase henn-1, which stabilizes the siRNAs. Association with 26G- siRNAs is required for the biogenesis of secondary 22G-siRNAs (a class of 22 nucleotide siRNAs that possess a triphosphorylated guan [...] | 0.927 |
alg-1 | eri-1 | F48F7.1b.1 | T07A9.5b.1 | Protein argonaute; Belongs to the argonaute family. | 3'-5' exonuclease eri-1; RNA exonuclease that acts as a negative regulator of RNA interference (RNAi). Probably acts by degrading the 3'-overhangs of short interfering RNAs (siRNAs). Its tissue specificity may help explain the inefficiency of neuronal RNAi. | 0.703 |
alg-1 | pash-1 | F48F7.1b.1 | T22A3.5a.1 | Protein argonaute; Belongs to the argonaute family. | PArtner of DroSHa (DRSH-1 interactor). | 0.668 |
alg-1 | rde-1 | F48F7.1b.1 | K08H10.7.1 | Protein argonaute; Belongs to the argonaute family. | RNA interference promoting factor RDE-1. | 0.805 |
alg-1 | rde-4 | F48F7.1b.1 | T20G5.11.1 | Protein argonaute; Belongs to the argonaute family. | RNA interference promoting factor. | 0.937 |
alg-1 | rrf-3 | F48F7.1b.1 | F10B5.7.1 | Protein argonaute; Belongs to the argonaute family. | RNA-dependent RNA polymerase Family. | 0.426 |
alg-1 | stau-1 | F48F7.1b.1 | F55A4.5.1 | Protein argonaute; Belongs to the argonaute family. | STAUfen (DsRNA binding protein) homolog. | 0.429 |
alg-2 | alg-1 | T07D3.7a.1 | F48F7.1b.1 | Protein argonaute; Belongs to the argonaute family. | Protein argonaute; Belongs to the argonaute family. | 0.941 |
alg-2 | dcr-1 | T07D3.7a.1 | K12H4.8.2 | Protein argonaute; Belongs to the argonaute family. | Death-promoting deoxyribonuclease; Involved in cleaving double-stranded RNA in the RNA interference (RNAi) pathway. It produces 21 to 23 bp dsRNAs (siRNAs) which target the selective destruction of homologous RNAs. Seems to process the precursor of the small temporal RNA let-7 which is involved in developmental timing. Belongs to the helicase family. Dicer subfamily. | 0.981 |
alg-2 | ergo-1 | T07D3.7a.1 | R09A1.1a.1 | Protein argonaute; Belongs to the argonaute family. | Piwi-like protein ergo-1; Argonaute protein required for gene silencing in the endogenous RNA interference (RNAi) pathway. Involved in the 26G RNAi pathway and associates with both unmethylated and methylated 26G small interfering RNAs (26G- siRNAs), which are a class of 26 nucleotide siRNAs that possess a guanine residue at the 5'-end. Associated 26G-siRNAs are methylated by the methyltransferase henn-1, which stabilizes the siRNAs. Association with 26G- siRNAs is required for the biogenesis of secondary 22G-siRNAs (a class of 22 nucleotide siRNAs that possess a triphosphorylated guan [...] | 0.930 |
alg-2 | eri-1 | T07D3.7a.1 | T07A9.5b.1 | Protein argonaute; Belongs to the argonaute family. | 3'-5' exonuclease eri-1; RNA exonuclease that acts as a negative regulator of RNA interference (RNAi). Probably acts by degrading the 3'-overhangs of short interfering RNAs (siRNAs). Its tissue specificity may help explain the inefficiency of neuronal RNAi. | 0.700 |
alg-2 | pash-1 | T07D3.7a.1 | T22A3.5a.1 | Protein argonaute; Belongs to the argonaute family. | PArtner of DroSHa (DRSH-1 interactor). | 0.577 |
alg-2 | rde-1 | T07D3.7a.1 | K08H10.7.1 | Protein argonaute; Belongs to the argonaute family. | RNA interference promoting factor RDE-1. | 0.803 |
alg-2 | rde-4 | T07D3.7a.1 | T20G5.11.1 | Protein argonaute; Belongs to the argonaute family. | RNA interference promoting factor. | 0.929 |
alg-2 | rrf-3 | T07D3.7a.1 | F10B5.7.1 | Protein argonaute; Belongs to the argonaute family. | RNA-dependent RNA polymerase Family. | 0.515 |
dcr-1 | alg-1 | K12H4.8.2 | F48F7.1b.1 | Death-promoting deoxyribonuclease; Involved in cleaving double-stranded RNA in the RNA interference (RNAi) pathway. It produces 21 to 23 bp dsRNAs (siRNAs) which target the selective destruction of homologous RNAs. Seems to process the precursor of the small temporal RNA let-7 which is involved in developmental timing. Belongs to the helicase family. Dicer subfamily. | Protein argonaute; Belongs to the argonaute family. | 0.991 |
dcr-1 | alg-2 | K12H4.8.2 | T07D3.7a.1 | Death-promoting deoxyribonuclease; Involved in cleaving double-stranded RNA in the RNA interference (RNAi) pathway. It produces 21 to 23 bp dsRNAs (siRNAs) which target the selective destruction of homologous RNAs. Seems to process the precursor of the small temporal RNA let-7 which is involved in developmental timing. Belongs to the helicase family. Dicer subfamily. | Protein argonaute; Belongs to the argonaute family. | 0.981 |