STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
calu-1CALUmenin (Calcium-binding protein) homolog. (314 aa)    
Predicted Functional Partners:
C47E12.3
alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.
   
  
 0.812
tag-353
Ubiquitin-like domain-containing protein.
      
 0.810
Y56A3A.2
Peptidase_M50 domain-containing protein.
      
 0.810
nucb-1
NUCleoBindin homolog.
   
 
 0.797
crt-1
Calreticulin; Molecular calcium-binding chaperone promoting folding, oligomeric assembly and quality control in the ER via the calreticulin/calnexin cycle (By similarity). This lectin may interact transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER (By similarity). Probably by controlling the folding of extracellular matrix protein unc-52/Perlecan, may play a role in the formation of fibrous organelles, a hemidesmosome-like structure attaching muscles to the epidermis. Protects dopaminergic neurons against oxidative stress-induced neurodegen [...]
   
 
 0.772
rla-0
60S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10.
   
 
 0.714
Y54G2A.18
4D656.
   
  
 0.711
cdkr-3
CDK5RAP3-like protein; Potential regulator of CDK5 activity.
   
  
 0.706
nud-1
CS domain-containing protein.
   
  
 0.704
col-84
Col_cuticle_N domain-containing protein.
    
 
 0.695
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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