node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C34E11.4 | R02F2.1 | C34E11.4.1 | R02F2.1b.3 | Uncharacterized protein. | CYCLIN domain-containing protein; Belongs to the cyclin family. | 0.619 |
C34E11.4 | T08D2.7 | C34E11.4.1 | T08D2.7.1 | Uncharacterized protein. | Uncharacterized protein; Belongs to the protein kinase superfamily. | 0.411 |
C34E11.4 | cdc-6 | C34E11.4.1 | C43E11.10.1 | Uncharacterized protein. | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | 0.758 |
C34E11.4 | cye-1 | C34E11.4.1 | C37A2.4a.1 | Uncharacterized protein. | G1/S-specific cyclin-E; Essential for the control of the cell cycle at the G1/S (start) transition. In association with cdk-2, regulates proliferation, quiescent state and cell fate during the development of several cell lineages. In the embryo, initiates the establishment of cell polarity through the recruitment of the centrosomal proteins spd-2 and spd-5 during prophase. During the development of the vulva, controls the onset of vulval cell terminal differentiation by controlling the duration of G1 phase. During hypoderm development at early larval stages, controls syncytial fate of [...] | 0.596 |
C34E11.4 | fzr-1 | C34E11.4.1 | ZK1307.6.1 | Uncharacterized protein. | WD_REPEATS_REGION domain-containing protein. | 0.741 |
C34E11.4 | fzy-1 | C34E11.4.1 | ZK177.6.1 | Uncharacterized protein. | WD repeat-containing protein fzy-1; Plays a role in metaphase-anaphase transition during meiosis I. Required for embryonic anterior-posterior axis formation ; Belongs to the WD repeat CDC20/Fizzy family. | 0.741 |
R02F2.1 | C34E11.4 | R02F2.1b.3 | C34E11.4.1 | CYCLIN domain-containing protein; Belongs to the cyclin family. | Uncharacterized protein. | 0.619 |
R02F2.1 | T08D2.7 | R02F2.1b.3 | T08D2.7.1 | CYCLIN domain-containing protein; Belongs to the cyclin family. | Uncharacterized protein; Belongs to the protein kinase superfamily. | 0.836 |
R02F2.1 | Y49E10.10 | R02F2.1b.3 | Y49E10.10.1 | CYCLIN domain-containing protein; Belongs to the cyclin family. | Uncharacterized protein. | 0.675 |
R02F2.1 | cdc-6 | R02F2.1b.3 | C43E11.10.1 | CYCLIN domain-containing protein; Belongs to the cyclin family. | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | 0.684 |
R02F2.1 | cdk-4 | R02F2.1b.3 | F18H3.5b.1 | CYCLIN domain-containing protein; Belongs to the cyclin family. | Cyclin-dependent kinase 4 homolog; Serine/threonine-protein kinase which, in association with cyclin D-like protein cyd-1, is required for the progression through the G1 phase of the cell cycle during postembryonic development by phosphorylating and inhibiting lin-35 and fzr-1. In complex with cyd-1, involved in sex determination during gonadogenesis by regulating the asymmetric division of the somatic gonadal precursor cell (SGP). | 0.619 |
R02F2.1 | cye-1 | R02F2.1b.3 | C37A2.4a.1 | CYCLIN domain-containing protein; Belongs to the cyclin family. | G1/S-specific cyclin-E; Essential for the control of the cell cycle at the G1/S (start) transition. In association with cdk-2, regulates proliferation, quiescent state and cell fate during the development of several cell lineages. In the embryo, initiates the establishment of cell polarity through the recruitment of the centrosomal proteins spd-2 and spd-5 during prophase. During the development of the vulva, controls the onset of vulval cell terminal differentiation by controlling the duration of G1 phase. During hypoderm development at early larval stages, controls syncytial fate of [...] | 0.655 |
R02F2.1 | fzr-1 | R02F2.1b.3 | ZK1307.6.1 | CYCLIN domain-containing protein; Belongs to the cyclin family. | WD_REPEATS_REGION domain-containing protein. | 0.744 |
R02F2.1 | fzy-1 | R02F2.1b.3 | ZK177.6.1 | CYCLIN domain-containing protein; Belongs to the cyclin family. | WD repeat-containing protein fzy-1; Plays a role in metaphase-anaphase transition during meiosis I. Required for embryonic anterior-posterior axis formation ; Belongs to the WD repeat CDC20/Fizzy family. | 0.743 |
R02F2.1 | pct-1 | R02F2.1b.3 | C07G1.3c.2 | CYCLIN domain-containing protein; Belongs to the cyclin family. | Cyclin-dependent kinase 17; Serine/threonine-protein kinase, which, in association with cyy-1, regulates the trafficking of synaptic vesicles in the DA9 motor neuron and probably also in the DD motor neurons and in RIA interneurons. | 0.619 |
R02F2.1 | shk-1 | R02F2.1b.3 | ZK1321.2c.1 | CYCLIN domain-containing protein; Belongs to the cyclin family. | Potassium voltage-gated channel protein shk-1; Mediates the voltage-dependent potassium ion permeability of excitable membranes. Has an important role in repolarization and in regulating the pattern of action potential firing. Isoform a expresses currents in a more depolarized voltage range than isoform d. | 0.637 |
T08D2.7 | C34E11.4 | T08D2.7.1 | C34E11.4.1 | Uncharacterized protein; Belongs to the protein kinase superfamily. | Uncharacterized protein. | 0.411 |
T08D2.7 | R02F2.1 | T08D2.7.1 | R02F2.1b.3 | Uncharacterized protein; Belongs to the protein kinase superfamily. | CYCLIN domain-containing protein; Belongs to the cyclin family. | 0.836 |
T08D2.7 | cdc-6 | T08D2.7.1 | C43E11.10.1 | Uncharacterized protein; Belongs to the protein kinase superfamily. | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | 0.585 |
T08D2.7 | cdk-4 | T08D2.7.1 | F18H3.5b.1 | Uncharacterized protein; Belongs to the protein kinase superfamily. | Cyclin-dependent kinase 4 homolog; Serine/threonine-protein kinase which, in association with cyclin D-like protein cyd-1, is required for the progression through the G1 phase of the cell cycle during postembryonic development by phosphorylating and inhibiting lin-35 and fzr-1. In complex with cyd-1, involved in sex determination during gonadogenesis by regulating the asymmetric division of the somatic gonadal precursor cell (SGP). | 0.518 |