STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cnnm-2Metal transporter cnnm-2; Probable metal transporter. Probably acts redundantly with the other metal transport proteins cnnm-1, cnnm-3, cnnm-4 and cnnm-5 to regulate Mg(2+) homeostasis. (762 aa)    
Predicted Functional Partners:
ZC116.3
Cubilin homolog; Cotransporter which plays a role in lipoprotein, vitamin and iron metabolism, by facilitating their uptake.
      
 0.741
gmps-1
Probable GMP synthase [glutamine-hydrolyzing].
  
 
 0.712
atic-1
MGS domain-containing protein.
  
 
 0.646
tag-4
Uncharacterized protein.
      
 0.640
T19D2.2
Putative prenylated protein tyrosine phosphatase.
   
 
 0.563
nfx-1
Transcriptional repressor NF-X1 homolog; May play a role in transcription regulation; Belongs to the NFX1 family.
      
 0.520
cnnm-4
Metal transporter cnnm-4; Probable metal transporter. Probably acts redundantly with the other metal transport proteins cnnm-1, cnnm-2, cnnm-3 and cnnm-5 to regulate Mg(2+) homeostasis.
  
   
0.466
aak-1
5'-AMP-activated protein kinase catalytic subunit alpha-1; Probably does not act as a sensor that couples lifespan to information about energy levels and insulin-like signals. Together with aak-2, involved in the establishment of germline stem cell (GSC) quiescence during dauer development. Plays a role in the maintenance of glycogen stores which are necessary for resistance to hyperosmotic stress.
   
  
 0.466
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.