STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dhs-14DeHydrogenases, Short chain; Protein DHS-14 (dhs-14) mRNA, complete cds (279 aa)    
Predicted Functional Partners:
lin-39
Homeobox protein lin-39; Transcription factor that binds to the consensus 5'- TGATNNAT(G/T)(G/A)-3' PBC/Hox motif of target genes to regulate gene expression. Binds to the consensus PBC/Hox motif lineage enhancer region of sem-2 to promote cell fate specification in the postembryonic mesoderm (also known as the M lineage). Regulates the expression of mig-13 which controls the asymmetric distribution of actin cytoskeleton-binding protein cor-1 in Q neuroblasts. This in turn controls the polarity migration of Q neuroblasts and the subsequent mid-body region-specific development; Belongs [...]
    
   0.756
col-146
COLlagen; Protein COL-146 (col-146) mRNA, complete cds
   
  
 0.712
T21G5.1
Tyrosine-protein kinase; Protein T21G5.1 (T21G5.1) mRNA, complete cds
   
 
 0.710
gska-3
Glycogen Synthase Kinase Alpha subunit; Protein GSKA-3 (gska-3) mRNA, complete cds
   
 
 0.709
B0280.11
Putative tyrosine-protein phosphatase B0280.11; Protein B0280.11 (B0280.11) mRNA, complete cds
      
 0.707
C50F4.6
Protein C50F4.6 (C50F4.6) mRNA, complete cds
      
 0.707
T25B9.6
Protein T25B9.6 (T25B9.6) mRNA, complete cds
      
 0.707
Y57G11C.6
Protein Y57G11C.6 (Y57G11C.6) mRNA, complete cds
      
 0.707
C05G5.5
Metalloprotease TIKI homolog; Metalloprotease; Belongs to the TIKI family
    
   0.705
C09B8.4
Protein C09B8.4 (C09B8.4) mRNA, complete cds
      
 0.705
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Caenorhabditis elegans, Rhabditis elegans, roundworm
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